8rm7_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HUMAN ANDROGEN RECEPTOR DNA BINDING DOMAIN BOUND TO ITS RESPONSE ELEMENT: MMTV-177 GRE/ARE
reference	Van Eynde et al. 'J.Steroid 241 106499 2024
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	8rm6_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8rm7_A interface=16,25,26,30, qktclicgdeasgahYgaltcgscKVffkRaaegkqkylcasrndctidkfrrkncpscrlrkcyeagmtlga > 8rm7_B interface=16,25,26,29,30, qktclicgdeasgahYgaltcgscKVffKRaaegkqkylcasrndctidkfrrkncpscrlrkcyeagmtlga
interface signature	YKVR/YKVKR

Estimated binding specificities ?

readout + contact

# IC=7.497 IC/col=0.682 n_of_columns=11

specificity:

A |   0  16  96   0  68  24  24  24   6   0   6
C |   0   6   0  96  13  24  24  24   6   0  13
G |   0  13   0   0   6  24  24  24   9  96   0
T |  96  61   0   0   9  24  24  24  75   0  77

scan!

home
updated Fri Aug 1 16:32:07 2025