8rm6_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HUMAN ANDROGEN RECEPTOR DNA BINDING DOMAIN BOUND TO ITS RESPONSE ELEMENT: C3(1)ARE
reference	Van Eynde et al. 'J.Steroid 241 106499 2024
experiment	X-ray (resolution=2.05, R-factor=0.223)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	1r4i_AB 8rm6_AB 8rm7_AB
redundant complexes	1r4i_B 8rm7_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8rm6_A interface=25,26,30, qktclicgdeasgahygaltcgscKVffkRaaegkqkylcasrndctidkfrrkncpscrlrkcyeagmtlga
interface signature	KVR

Estimated binding specificities ?

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# IC=4.007 IC/col=0.668 n_of_columns=6

specificity:

A |  67   9  24  69   0  96
C |   9   9  24   9  96   0
G |   9  67  24   9   0   0
T |  11  11  24   9   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --EAKG--KTRG--   L     +-----------------------------4umm_A    
                       +-4 
  ----KGVT--RG--   L   ! +-----------------------------2c7a_B    
                       ! 
  CAECKG--KGRG--   L --5                       +-----1cit_A    
                       !     +-----------------2 
  --ECKGAG--RG--   L   !     !                 +-----4ond_A    
                       +-----3 
  --ECKGAGKGRG--   L         !                      +1hcq_E    
                             +----------------------1 
  --ECKGAG--KTRG   L                                +4aa6_B

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updated Sun Jan 11 01:16:00 2026