8sfn_A : 3D-footprint complex

structure name	WT CRISPR-CAS12A WITH A 16BP R-LOOP AND NONTARGET STRAND IN THE RUVC ACTIVE SITE.
experiment	NMR
reference complex	8sfh_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sfn_A interface=14,83,87,92,167,175,178,273,279,382,383,386,513,514,517,543,546,594,595,597,598,599,602,706,779,869,878,879,990,991,994,998,1048,1049,1061,1062,1063,1162,1163,1164,1286,1290, mtqfegftnlyqvSktlrfelipqgktlkhiqeqgfieedkarndhykelkpiidriyktyadqclqlvqldwenlsaaidsYrkeKteetRnalieeqatyrnaihdyfigrtdnltdainkrhaeiykglfkaelfngkvlkqlgtvtttehenallrsfdkftTyfsgfyeNrkNvfsaedistaiphrivqdnfpkfkenchiftrlitavpslrehfenvkkaigifvstsieevfsfpfynqlltqtqidlynqllggisreagteKikglnEvlnlaiqkndetahiiaslphrfiplfkqilsdrntlsfileefksdeeviqsfckyktllrnenvletaealfnelnsidlthifishkkletissalcdhWDtlRnalyerriselksakekvqrslkhedinlqeiisaagkelseafkqktseilshahaaldqplpttlkkqeekeilksqldsllglyhlldwfavdesnevdpefsarltgiklemepslsfynkaRNyaTkkpysvekfklnfqmptlasgwdvnKekNngailfvknglyylgimpkqkgrykalsfeptektsegfdkmyydyfPDaAKMipKcstqlkavtahfqthttpillsnnfiepleitkeiydlnnpekepkkfqtayakktgdqkgyrealckwidftrdflskytkttsidlsslrpssqykdlgeyYaelnpllyhisfqriaekeimdavetgklylfqiynkdfakghhgkpnlhtlywtglfspenlaktsiklngQaelfyrpksrmkrmahrlgekmlnkklkdqktpipdtlyqelydyvnhrlshdlsdearallpnvitkevsheiikdrrftsdkfffhvPitlnyqaaNSpskfnqrvnaylkehpetpiigidrgernliyitvidstgkileqrslntiqqfdyqkkldnrekervaarqawsvvgtikdlkqgylsqviheivdlmihyqavvvlenLNfgFkskRtgiaekavyqqfekmlidklnclvlkdypaekvggvlnpyqltdqftsfAKmgtqsgflfyvPAPytskidpltgfvdpfvwktiknhesrkhflegfdflhydvktgdfilhfkmnrnlsfqrglpgfmpawdivfeknetqfdakgtpfiagkrivpvienHRFtgryrdlypanelialleekgivfrdgsnilpkllenddshaidtmvalirsvlqmrnsnaatgedyinspvrdlngvcfdsrfqnpewpmdadangayhialkgqlllnhlkeskdlklqNgisNqdwlayiqelrn
interface signature	SYKRTNNKEWDRRNTKNPDAKMKYQPNSLNFRAKPAPHRFNN

Estimated binding specificities ?

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# IC=25.619 IC/col=1.025 n_of_columns=25

specificity:

A |  96   0   0  96   0   0   4  96   0   0   0  24  24   0   4   0  24   4   9  96   0   0  96  96  62
C |   0   0   0   0  96   0  72   0   0   0  96  24  24  96   4   0  24   7  67   0  96   0   0   0   9
G |   0  96   0   0   0  96  11   0   0   0   0  24  24   0   4   0  24   4   9   0   0   0   0   0   9
T |   0   0  96   0   0   0   9   0  96  96   0  24  24   0  84  96  24  81  11   0   0  96   0   0  16

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updated Mon Jun 29 10:57:45 2026