interface graph thumbnail
legend  pdf

structure nameWT CRISPR-CAS12A WITH A 20BP R-LOOP AND NONTARGET STRAND IN THE RUVC ACTIVE SITE.
experimentNMR
reference complex8sfh_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYKRTSNNTKENLQESWRNTKNPDAKMKYQPNSLFRAKTAPYRYN

Estimated binding specificities ?

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# IC=22.932 IC/col=0.955 n_of_columns=24 specificity:   
A |   0   0  96   0   0   5  96  24  24  84   0   0  24  24  83  83   0   0   0   0  84   5   0   4
C |   0   0   0   0   0   4   0  24  24   4   0   4  24  24   5   4   0   0  96  96   4   4   0   4
G |   0   0   0  96   0  83   0  24  24   4  96   1  24  24   4   4   0  96   0   0   4   4  96   5
T |  96  96   0   0  96   4   0  24  24   4   0  91  24  24   4   5  96   0   0   0   4  83   0  83
scan!

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updated Fri Sep 13 13:18:08 2024