8sfo_A : 3D-footprint complex

structure name	WT CRISPR-CAS12A WITH A 20BP R-LOOP AND NONTARGET STRAND IN THE RUVC ACTIVE SITE.
experiment	NMR
reference complex	8sfh_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sfo_A interface=14,83,87,92,167,170,175,178,187,273,279,282,283,286,372,376,382,513,514,534,543,546,594,595,597,598,599,602,706,779,807,816,817,928,932,936,986,987,990,1000,1001,1002,1105,1106,1228, mtqfegftnlyqvSktlrfelipqgktlkhiqeqgfieedkarndhykelkpiidriyktyadqclqlvqldwenlsaaidsYrkeKteetRnalieeqatyrnaihdyfigrtdnltdainkrhaeiykglfkaelfngkvlkqlgtvtttehenallrsfdkftTyfSgfyeNrkNvfsaedisTaiphrivqdnfpkfkenchiftrlitavpslrehfenvkkaigifvstsieevfsfpfynqlltqtqidlynqllggisreagteKikglnEvlNLaiQkndetahiiaslphrfiplfkqilsdrntlsfileefksdeeviqsfckyktllrnenvletaealfnelnsidlthifishkklEtisSalcdhWdtlrnalyerriselksakekvqrslkhedinlqeiisaagkelseafkqktseilshahaaldqplpttlkkqeekeilksqldsllglyhlldwfavdesnevdpefsarltgiklemepslsfynkaRNyatkkpysvekfklnfqmpTlasgwdvnKekNngailfvknglyylgimpkqkgrykalsfeptektsegfdkmyydyfPDaAKMipKcstqlkavtahfqthttpillsnnfiepleitkeiydlnnpekepkkfqtayakktgdqkgyrealckwidftrdflskytkttsidlsslrpssqykdlgeyYaelnpllyhisfqriaekeimdavetgklylfqiynkdfakghhgkpnlhtlywtglfspenlaktsiklngQaelfyrpksheiikdrrftsdkfffhvPitlnyqaaNSpskfnqrvnaylkehpetpiigidrgernliyitvidstgkileqrslntiqqfdyqkkldnrekervaarqawsvvgtikdlkqgylsqviheivdlmihyqavvvlenLnfgFkskRtgiaekavyqqfekmlidklnclvlkdypaekvggvlnpyqltdqftsfAKmgTqsgflfyvpAPYtskidpltgfvdpfvwktiknhesrkhflegfdflhydvktgdfilhfkmnrnlsfqrglpgfmpawdivfeknetqfdakgtpfiagkrivpvienhrftgRYrdlypanelialleekgivfrdgsnilpkllenddshaidtmvalirsvlqmrnsnaatgedyinspvrdlngvcfdsrfqnpewpmdadangayhialkgqlllnhlkeskdlklqngisNqdwlayiqelrn
interface signature	SYKRTSNNTKENLQESWRNTKNPDAKMKYQPNSLFRAKTAPYRYN

Estimated binding specificities ?

contact

# IC=23.186 IC/col=0.966 n_of_columns=24

specificity:

A |  96   0  80   5   0   0   0  96   5   6  24  24  96   0   5  24  24   0   5  96   0   0  96  96
C |   0  96   5   5   0   0  96   0   5   5  24  24   0  96   5  24  24   0  81   0  96   0   0   0
G |   0   0   6   5  96  96   0   0   5   5  24  24   0   0   5  24  24   0   5   0   0   0   0   0
T |   0   0   5  81   0   0   0   0  81  80  24  24   0   0  81  24  24  96   5   0   0  96   0   0

scan!

home
updated Sun Aug 3 02:54:30 2025