8sfo_A : 3D-footprint complex

structure name	WT CRISPR-CAS12A WITH A 20BP R-LOOP AND NONTARGET STRAND IN THE RUVC ACTIVE SITE.
experiment	NMR
reference complex	8sfh_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sfo_A interface=14,83,87,92,167,170,175,178,187,273,279,282,283,286,372,376,382,513,514,534,543,546,594,595,597,598,599,602,706,779,807,816,817,928,932,936,986,987,990,1000,1001,1002,1105,1106,1228, mtqfegftnlyqvSktlrfelipqgktlkhiqeqgfieedkarndhykelkpiidriyktyadqclqlvqldwenlsaaidsYrkeKteetRnalieeqatyrnaihdyfigrtdnltdainkrhaeiykglfkaelfngkvlkqlgtvtttehenallrsfdkftTyfSgfyeNrkNvfsaedisTaiphrivqdnfpkfkenchiftrlitavpslrehfenvkkaigifvstsieevfsfpfynqlltqtqidlynqllggisreagteKikglnEvlNLaiQkndetahiiaslphrfiplfkqilsdrntlsfileefksdeeviqsfckyktllrnenvletaealfnelnsidlthifishkklEtisSalcdhWdtlrnalyerriselksakekvqrslkhedinlqeiisaagkelseafkqktseilshahaaldqplpttlkkqeekeilksqldsllglyhlldwfavdesnevdpefsarltgiklemepslsfynkaRNyatkkpysvekfklnfqmpTlasgwdvnKekNngailfvknglyylgimpkqkgrykalsfeptektsegfdkmyydyfPDaAKMipKcstqlkavtahfqthttpillsnnfiepleitkeiydlnnpekepkkfqtayakktgdqkgyrealckwidftrdflskytkttsidlsslrpssqykdlgeyYaelnpllyhisfqriaekeimdavetgklylfqiynkdfakghhgkpnlhtlywtglfspenlaktsiklngQaelfyrpksheiikdrrftsdkfffhvPitlnyqaaNSpskfnqrvnaylkehpetpiigidrgernliyitvidstgkileqrslntiqqfdyqkkldnrekervaarqawsvvgtikdlkqgylsqviheivdlmihyqavvvlenLnfgFkskRtgiaekavyqqfekmlidklnclvlkdypaekvggvlnpyqltdqftsfAKmgTqsgflfyvpAPYtskidpltgfvdpfvwktiknhesrkhflegfdflhydvktgdfilhfkmnrnlsfqrglpgfmpawdivfeknetqfdakgtpfiagkrivpvienhrftgRYrdlypanelialleekgivfrdgsnilpkllenddshaidtmvalirsvlqmrnsnaatgedyinspvrdlngvcfdsrfqnpewpmdadangayhialkgqlllnhlkeskdlklqngisNqdwlayiqelrn
interface signature	SYKRTSNNTKENLQESWRNTKNPDAKMKYQPNSLFRAKTAPYRYN

Estimated binding specificities ?

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# IC=23.078 IC/col=0.962 n_of_columns=24

specificity:

A |  96   0  80   5   0   0   0  96   5   6  24  24  96   0   5  24  24   0   5  96   0   0  96  96
C |   0  96   5   6   0   0  96   0   6   5  24  24   0  96   6  24  24   0  80   0  96   0   0   0
G |   0   0   5   5  96  96   0   0   5   5  24  24   0   0   5  24  24   0   6   0   0   0   0   0
T |   0   0   6  80   0   0   0   0  80  80  24  24   0   0  80  24  24  96   5   0   0  96   0   0

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updated Mon Jun 29 10:58:53 2026