8sfo_A : 3D-footprint complex

structure name	WT CRISPR-CAS12A WITH A 20BP R-LOOP AND NONTARGET STRAND IN THE RUVC ACTIVE SITE.
experiment	NMR
reference complex	8sfh_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sfo_A interface=14,83,87,92,167,170,175,178,187,273,279,282,283,286,372,376,382,513,514,534,543,546,594,595,597,598,599,602,706,779,807,816,817,928,932,936,986,987,990,1000,1001,1002,1105,1106,1228, mtqfegftnlyqvSktlrfelipqgktlkhiqeqgfieedkarndhykelkpiidriyktyadqclqlvqldwenlsaaidsYrkeKteetRnalieeqatyrnaihdyfigrtdnltdainkrhaeiykglfkaelfngkvlkqlgtvtttehenallrsfdkftTyfSgfyeNrkNvfsaedisTaiphrivqdnfpkfkenchiftrlitavpslrehfenvkkaigifvstsieevfsfpfynqlltqtqidlynqllggisreagteKikglnEvlNLaiQkndetahiiaslphrfiplfkqilsdrntlsfileefksdeeviqsfckyktllrnenvletaealfnelnsidlthifishkklEtisSalcdhWdtlrnalyerriselksakekvqrslkhedinlqeiisaagkelseafkqktseilshahaaldqplpttlkkqeekeilksqldsllglyhlldwfavdesnevdpefsarltgiklemepslsfynkaRNyatkkpysvekfklnfqmpTlasgwdvnKekNngailfvknglyylgimpkqkgrykalsfeptektsegfdkmyydyfPDaAKMipKcstqlkavtahfqthttpillsnnfiepleitkeiydlnnpekepkkfqtayakktgdqkgyrealckwidftrdflskytkttsidlsslrpssqykdlgeyYaelnpllyhisfqriaekeimdavetgklylfqiynkdfakghhgkpnlhtlywtglfspenlaktsiklngQaelfyrpksheiikdrrftsdkfffhvPitlnyqaaNSpskfnqrvnaylkehpetpiigidrgernliyitvidstgkileqrslntiqqfdyqkkldnrekervaarqawsvvgtikdlkqgylsqviheivdlmihyqavvvlenLnfgFkskRtgiaekavyqqfekmlidklnclvlkdypaekvggvlnpyqltdqftsfAKmgTqsgflfyvpAPYtskidpltgfvdpfvwktiknhesrkhflegfdflhydvktgdfilhfkmnrnlsfqrglpgfmpawdivfeknetqfdakgtpfiagkrivpvienhrftgRYrdlypanelialleekgivfrdgsnilpkllenddshaidtmvalirsvlqmrnsnaatgedyinspvrdlngvcfdsrfqnpewpmdadangayhialkgqlllnhlkeskdlklqngisNqdwlayiqelrn
interface signature	SYKRTSNNTKENLQESWRNTKNPDAKMKYQPNSLFRAKTAPYRYN

Estimated binding specificities ?

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# IC=22.892 IC/col=0.954 n_of_columns=24

specificity:

A |   0   0  96   0   0   4  96  24  24  83   0   0  24  24  83  83   0   0   0   0  83   5   0   5
C |   0   0   0   0   0   5   0  24  24   4   0   5  24  24   4   4   0   0  96  96   4   4   0   4
G |   0   0   0  96   0  83   0  24  24   5  96   0  24  24   5   4   0  96   0   0   5   4  96   4
T |  96  96   0   0  96   4   0  24  24   4   0  91  24  24   4   5  96   0   0   0   4  83   0  83

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updated Tue Dec 17 19:30:40 2024