8ssq_A : 3D-footprint complex

structure name	ZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 4 (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=3.12, R-factor=0.241)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
redundant complexes	8ssr_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ssq_A interface=21,47,50,75,78,100,133,136,190,218,248, trphkcpdcdmafvtsgelvRhrrykhthekpfkcsmcdyasvevsKlkRhirshtgerpfqcslcsyasrdtyKlkRhmrthsgekpyecyicharftQsgtmkmhilqkhtenvakfhcphcdtviarksDlgVhlrkqhsyieqgkkcrycdavfheryaliqhqkshknekrfkcdqcdyacrqeRhmimhkrthtgekpyacshcdktfrqkQlldmhfkryhdpnfvpaafvcskcgktftRrntmarhadnca
interface signature	RKRKRQDVRQR

Estimated binding specificities ?

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# IC=15.821 IC/col=0.452 n_of_columns=35

specificity:

A |  24  12  13  14  52  14   6  45  13   0  27  24  24  24  24  24  24  24  13   1  31   9   0  96   4  14   0   0   2   0   0  13  22  24  24
C |  24  12  14  52  16  16   6  19  63  96  22  24  24  24  24  24  24  24  56  93  21   9  96   0   4  13   0   0   2  96   0  56  22  24  24
G |  24  12  56  16  14  52   6  16  10   0  22  24  24  24  24  24  24  24  14   1  23  67   0   0  84  56  96  96  88   0  96  14  22  24  24
T |  24  60  13  14  14  14  78  16  10   0  25  24  24  24  24  24  24  24  13   1  21  11   0   0   4  13   0   0   4   0   0  13  30  24  24

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updated Wed Dec 20 04:04:56 2023