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structure nameZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 4
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=3.12, R-factor=0.241)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
redundant complexes8ssr_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTERYESKRYKRQTRSDVQRHMQQLTRN

Estimated binding specificities ?

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# IC=28.501 IC/col=0.919 n_of_columns=31 specificity:   
A |   0   0   0   0   0   0   0   0   0   0   0  13   0   0  24  24  24  24  24  24  24  24   0   0  13  96   0   0   0   0  96
C |   0  96   0  96  96  96  96  96   0   0  96  13   0   0  24  24  24  24  24  24  24  24   0   0  13   0  96   0   0  96   0
G |  96   0  96   0   0   0   0   0   0  96   0  13  96  96  24  24  24  24  24  24  24  24  96  96  13   0   0   0  96   0   0
T |   0   0   0   0   0   0   0   0  96   0   0  57   0   0  24  24  24  24  24  24  24  24   0   0  57   0   0  96   0   0   0
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updated Wed Dec 18 19:31:29 2024