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structure nameZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 4
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=3.12, R-factor=0.241)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes7w1m_ABDEH
redundant complexes8ssr
reference complex7w1m_H
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTERYESKRYKRQTRSDVQRHMQQLTRN

Estimated binding specificities ?

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# IC=25.310 IC/col=0.816 n_of_columns=31 specificity:   
A |   4   0   1  80   4   0  74   0  16  24  24  24  24  24  24  24  24   6   0  96   3   0  96   0   0   4   0   0   0   0   2
C |   4   0   4   6   6   0   8  96  80  24  24  24  24  24  24  24  24  82  96   0   2  96   0   0   0   0   0   0  76   0  84
G |   4  96   0   4  21   0   8   0   0  24  24  24  24  24  24  24  24   6   0   0  89   0   0  96  96  91  96  96   0  96   4
T |  84   0  91   6  65  96   6   0   0  24  24  24  24  24  24  24  24   2   0   0   2   0   0   0   0   1   0   0  20   0   6
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updated Mon Jun 29 11:20:06 2026