8ssq_A : 3D-footprint complex

structure name	ZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 4 (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=3.12, R-factor=0.241)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
redundant complexes	8ssr_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ssq_A interface=15,18,21,25,44,46,47,50,74,75,78,100,103,130,132,133,136,188,190,191,194,216,218,219,247,248,250, trphkcpdcdmafvTsgElvRhrrYkhthekpfkcsmcdyasvEvSKlkRhirshtgerpfqcslcsyasrdtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhsyieqgkkcrycdavfheryaliqhqkshknekrfkcdqcdyacrQeRHmiMhkrthtgekpyacshcdktfrQkQLldmhfkryhdpnfvpaafvcskcgktfTRrNtmarhadnca
interface signature	TERYESKRYKRQTRSDVQRHMQQLTRN

Estimated binding specificities ?

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# IC=25.178 IC/col=0.812 n_of_columns=31

specificity:

A |   5   0   1  79   4   0  71   0  16  24  24  24  24  24  24  24  24   7   0  96   2   0  96   0   0   5   0   0   0   0   4
C |   4   0   4   4   8   0  10  96  79  24  24  24  24  24  24  24  24  81  96   0   2  96   0   0   0   0   0   0  81   0  82
G |   4  96   0   6  15   0   8   0   1  24  24  24  24  24  24  24  24   6   0   0  89   0   0  96  96  91  96  96   0  96   4
T |  83   0  91   7  69  96   7   0   0  24  24  24  24  24  24  24  24   2   0   0   3   0   0   0   0   0   0   0  15   0   6

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updated Mon Aug 4 02:13:02 2025