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structure nameZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 4
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=3.12, R-factor=0.241)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes7w1m_ABDEH
redundant complexes8ssr
reference complex7w1m_H
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTERYESKRYKRQTRSDVQRHMQQLTRN

Estimated binding specificities ?

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# IC=25.511 IC/col=0.823 n_of_columns=31 specificity:   
A |   2   0   0  78   4   0  70   0  14  24  24  24  24  24  24  24  24   6   0  96   2   0  96   0   0   6   0   0   0   0   4
C |   2   0   4   6   6   0  10  96  82  24  24  24  24  24  24  24  24  80  96   0   2  96   0   0   0   0   0   0  86   0  82
G |   4  96   0   6  18   0  12   0   0  24  24  24  24  24  24  24  24   6   0   0  90   0   0  96  96  90  96  96   0  96   6
T |  88   0  92   6  68  96   4   0   0  24  24  24  24  24  24  24  24   4   0   0   2   0   0   0   0   0   0   0  10   0   4
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updated Sat Jan 10 01:55:03 2026