8sss_A : 3D-footprint complex

structure name	ZNFS 1-7 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 23MER (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=0.201)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5kkq_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sss_A interface=13,15,16,19,44,69,70,72,75,79,98,101,104,126,128,129,132,154,157,184,186,187,190, tfqcelcsytcpRrSNldRhmkshtderphkchlcgrafrtvtLlrnhlnthtgtrphkcpdcdmafvTSgElvRhrrYkhthekpfkcsmcdyasvEvsKlkRhirshtgerpfqcslcsyasrDtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhs
interface signature	RSNRLTSERYEKRDYKRQTRSDV

Estimated binding specificities ?

readout + contact

# IC=24.218 IC/col=1.101 n_of_columns=22

specificity:

A |   7   0   0   0  96  84  87  24   6   0   0   0   0   7   0   0   0   0   3   3   0   3
C |  81  96   0  96   0   3   3  24   3  96   0  96  96  88  96  96   0   0  86  76   0   5
G |   3   0   0   0   0   3   3  24  84   0  96   0   0   0   0   0   0  96   0   3  96  81
T |   5   0  96   0   0   6   3  24   3   0   0   0   0   1   0   0  96   0   7  14   0   7

scan!

home
updated Sun Aug 3 03:12:13 2025