interface graph thumbnail
legend  pdf

structure nameZNFS 1-7 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 23MER
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.201)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kkq_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNRLTSERYEKRDYKRQTRSDV

Estimated binding specificities ?

readout + contactlogo
# IC=24.190 IC/col=1.100 n_of_columns=22 specificity:   
A |   7   0   0   0  96  88  84  24   6   0   0   0   0   7   0   0   0   0   3   6   0   3
C |  83  96   0  96   0   0   3  24   3  96   0  96  96  89  96  96   0   0  84  72   0   7
G |   3   0   0   0   0   5   3  24  84   0  96   0   0   0   0   0   0  96   0   3  96  79
T |   3   0  96   0   0   3   6  24   3   0   0   0   0   0   0   0  96   0   9  15   0   7
scan!

home
updated Fri Sep 13 13:33:57 2024