interface graph thumbnail
legend  pdf

structure nameZNFS 1-7 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 23MER
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.201)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNRLTSERYEKRDYKRQTRSDV

Estimated binding specificities ?

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# IC=24.008 IC/col=1.091 n_of_columns=22 specificity:   
A |   7   0   0   0  96  85  87  24   5   0   0   0   0   3   0   0   0   0   3   3   0   3
C |  79  96   0  96   0   3   3  24   3  96   0  96  96  92  96  96   0   0  81  74   0   7
G |   7   0   0   0   0   3   3  24  85   0  96   0   0   1   0   0   0  96   3   9  96  78
T |   3   0  96   0   0   5   3  24   3   0   0   0   0   0   0   0  96   0   9  10   0   8
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updated Tue Dec 17 19:48:10 2024