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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 5' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.79, R-factor=0.197)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=13.109 IC/col=0.655 n_of_columns=20 specificity:   
A |  80  16  24  12   0   0   0  96   0  96  24  24  24  24   8   0   0  24  24  12
C |   4  56  24   8   0   0   0   0  96   0  24  24  24  24   8  96  96  24  24  68
G |   8  12  24   8  96   0  96   0   0   0  24  24  24  24  72   0   0  24  24   8
T |   4  12  24  68   0  96   0   0   0   0  24  24  24  24   8   0   0  24  24   8
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updated Sun Aug 3 03:25:36 2025