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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 3' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.45, R-factor=0.224)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.727 IC/col=0.701 n_of_columns=21 specificity:   
A |  73  13  24   9   0   0   0  96   0  96  24  24  24  24  24   0   0  24  91   9  86
C |   4  59  24  10   0   0   0   0  96   0  24  24  24  24  24  96  96  24   0  77   0
G |   9  15  24   9  96   0  96   0   0   0  24  24  24  24  24   0   0  24   1   4   4
T |  10   9  24  68   0  96   0   0   0   0  24  24  24  24  24   0   0  24   4   6   6
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updated Fri Sep 13 13:46:00 2024