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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 3' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.45, R-factor=0.224)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.293 IC/col=0.728 n_of_columns=21 specificity:   
A |   0   7   0  24   0   0  24  24  24  24  24   0   0   0   0  96   0  62  24   5  11
C |   5   5   0  24   0   0  24  24  24  24  24   0   0   0  96   0  96  13  24  11   5
G |   0  79   0  24  96  96  24  24  24  24  24   0  96   0   0   0   0  16  24  67   5
T |  91   5  96  24   0   0  24  24  24  24  24  96   0  96   0   0   0   5  24  13  75
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updated Sun Aug 3 03:25:59 2025