8tiq_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 3' TERMINAL PHOSPHATES. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=2.45, R-factor=0.224)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tiq_C interface=56,57,58,60,61,64,94,164,165,167,169,170,173,174,200, nsprivqsndlteaayslsrdqkrmlylfvdqirkshdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.850 IC/col=0.707 n_of_columns=21

specificity:

A |  81   9  24   9   0   0   0  96   0  96  24  24  24  24  24   0   0  24  91  14  91
C |   7  64  24  11   0   0   0   0  96   0  24  24  24  24  24  96  96  24   1  67   0
G |   4  14  24  14  96   0  96   0   0   0  24  24  24  24  24   0   0  24   0   6   4
T |   4   9  24  62   0  96   0   0   0   0  24  24  24  24  24   0   0  24   4   9   1

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updated Sat Jan 10 02:12:06 2026