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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 5' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.217)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.874 IC/col=0.708 n_of_columns=21 specificity:   
A |   0   4  24  24   0   0   4  24  24  24  24   0   0   0   0  96   0  82  24  13   4
C |   5  13  24  24   0   0  82  24  24  24  24   0   0   0  96   0  96   0  24  10   9
G |   0  68  24  24  92  96   4  24  24  24  24   0  96   0   0   0   0   4  24  64   4
T |  91  11  24  24   4   0   6  24  24  24  24  96   0  96   0   0   0  10  24   9  79
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updated Tue Dec 17 20:02:03 2024