8tir_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 5' TERMINAL PHOSPHATES. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.11, R-factor=0.217)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tir_C interface=56,57,58,60,61,64,94,164,165,167,169,170,173,174,200, nsprivqsndlteaayslsrdqkrmlylfvdqirkshdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffinrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.479 IC/col=0.689 n_of_columns=21

specificity:

A |  87  14  24   8   0   0   0  96   0  96  24  24  24  24   8   0   5  24  24   8  92
C |   1  58  24   8   0   0   0   0  96   0  24  24  24  24   8  96  91  24  24  70   0
G |   4  12  24  10  96   0  96   0   0   0  24  24  24  24  75   0   0  24  24   8   4
T |   4  12  24  70   0  96   0   0   0   0  24  24  24  24   5   0   0  24  24  10   0

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updated Sat Jan 10 02:12:25 2026