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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 5' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.217)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex7rva_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=7.677 IC/col=0.256 n_of_columns=30 specificity:   
A |  24  24  24  21  49  18  24  16  10   0   0  96   4  85  24  24  24  24  18  10  18  20  22  14  45  21  24  24  24  24
C |  24  24  24  23  15  42  24  16   8   0   0   0  88   5  24  24  24  24  18  63  42  34  20  54  19  23  24  24  24  24
G |  24  24  24  31  17  18  24  16  70   0  96   0   2   3  24  24  24  24  42  13  18  22  20  14  16  31  24  24  24  24
T |  24  24  24  21  15  18  24  48   8  96   0   0   2   3  24  24  24  24  18  10  18  20  34  14  16  21  24  24  24  24
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updated Tue Dec 19 05:00:35 2023