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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 3' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.54, R-factor=0.255)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=13.754 IC/col=0.724 n_of_columns=19 specificity:   
A |   4   0   9  24  24   0   0   4  24  24  24  24   4   0   0   0  96   0  76
C |  72   4  11  24  24   0   0  72  24  24  24  24   0   0   0  96   0  96  12
G |   9   0  67  24  24  96  96   4  24  24  24  24   4  96   0   0   0   0   4
T |  11  92   9  24  24   0   0  16  24  24  24  24  88   0  96   0   0   0   4
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updated Sun Aug 3 03:26:38 2025