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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 3' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.54, R-factor=0.255)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=13.986 IC/col=0.736 n_of_columns=19 specificity:   
A |   6   0   0   0  96   0  96  24  24  24  24   6   0   0  24  24  12  90   6
C |   6   0   0   0   0  96   0  24  24  24  24   6  96  96  24  24  66   0   6
G |  12  96   0  96   0   0   0  24  24  24  24  78   0   0  24  24   6   6  72
T |  72   0  96   0   0   0   0  24  24  24  24   6   0   0  24  24  12   0  12
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updated Sat Jan 10 02:12:45 2026