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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.84, R-factor=0.209)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.960 IC/col=0.712 n_of_columns=21 specificity:   
A |   0  12  53  24   0   0   8  24  24  24  24   0   0   0   0  96   0  79  24   3  10
C |   2   5   5  24   0   0  32  24  24  24  24   0   0   0  96   0  96   3  24  15   3
G |   0  76  25  24  96  96  49  24  24  24  24   0  96   0   0   0   0   9  24  50   1
T |  94   3  13  24   0   0   7  24  24  24  24  96   0  96   0   0   0   5  24  28  82
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updated Sun Aug 3 03:26:54 2025