8tit_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=2.84, R-factor=0.209)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	7rva_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tit_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=7.603 IC/col=0.262 n_of_columns=29

specificity:

A |  24  24  24  24  18  15  17  42  22  18   7  19  24  24  24  24   6   2   2   0  96   8  49  24  19  18  24  24  24
C |  24  24  24  24  42  15  15  18  20  18   8  38  24  24  24  24   6   2   1  96   0  72  17  24  20  18  24  24  24
G |  24  24  24  24  18  15  49  18  34  42  74  20  24  24  24  24   6  90   1   0   0   8  15  24  38  18  24  24  24
T |  24  24  24  24  18  51  15  18  20  18   7  19  24  24  24  24  78   2  92   0   0   8  15  24  19  42  24  24  24

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updated Tue Dec 19 05:01:02 2023