8tit_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=2.84, R-factor=0.209)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tit_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.848 IC/col=0.707 n_of_columns=21

specificity:

A |   0   4  58  24   0   0   6  24  24  24  24   0   0   0   0  96   0  68  24  12   6
C |   2   6  14  24   0   0  28  24  24  24  24   0   0   0  96   0  96   8  24   8   6
G |   0  82   8  24  96  96  54  24  24  24  24   0  96   0   0   0   0  12  24  62   4
T |  94   4  16  24   0   0   8  24  24  24  24  96   0  96   0   0   0   8  24  14  80

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updated Tue Dec 17 20:02:48 2024