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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.84, R-factor=0.209)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=13.824 IC/col=0.658 n_of_columns=21 specificity:   
A |  80  24  24   6   0   0   0  96   0  96  24  24  24  24   9   0   0  24  18  13  93
C |   6  24  24  16   0   0   0   0  96   0  24  24  24  24  48  96  96  24  11  64   1
G |   6  24  24   9  96   0  96   0   0   0  24  24  24  24  34   0   0  24  20   8   2
T |   4  24  24  65   0  96   0   0   0   0  24  24  24  24   5   0   0  24  47  11   0
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updated Fri Sep 13 13:46:42 2024