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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.84, R-factor=0.209)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.160 IC/col=0.722 n_of_columns=21 specificity:   
A |   0   7  63  24   0   0   7  24  24  24  24   0   0   0   0  96   0  75  24   5   9
C |   2   7  13  24   0   0  17  24  24  24  24   0   0   0  96   0  96   6  24  12   7
G |   0  80  10  24  96  96  65  24  24  24  24   0  96   0   0   0   0  10  24  69   5
T |  94   2  10  24   0   0   7  24  24  24  24  96   0  96   0   0   0   5  24  10  75
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updated Mon Jun 29 11:38:56 2026