8tiu_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 3' TERMINAL PHOSPHATES. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.90, R-factor=0.200)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tiu_C interface=56,57,58,60,61,64,94,164,165,167,169,170,173,174,200, nsprivqsndlteaayslsrdqkrmlylfvdqirkshdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdit
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.158 IC/col=0.674 n_of_columns=21

specificity:

A |  75  10  24   6   0   0   0  96   0  96  24  24  24  24  24   0   0  24  24   3  89
C |   6  53  24   3   0   0   0   0  96   0  24  24  24  24   8  96  96  24  24  78   1
G |   9  20  24  12  96   0  96   0   0   0  24  24  24  24  54   0   0  24  24   9   6
T |   6  13  24  75   0  96   0   0   0   0  24  24  24  24  10   0   0  24  24   6   0

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updated Sat Jan 10 02:13:28 2026