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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 3' TERMINAL PHOSPHATES.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.90, R-factor=0.200)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.222 IC/col=0.677 n_of_columns=21 specificity:   
A |  76   9  24   6   0   0   0  96   0  96  24  24  24  24  13   0   0  24  24   6  82
C |   6  62  24   8   0   0   0   0  96   0  24  24  24  24   9  96  96  24  24  79   5
G |   8  16  24   6  96   0  96   0   0   0  24  24  24  24  66   0   0  24  24   8   6
T |   6   9  24  76   0  96   0   0   0   0  24  24  24  24   8   0   0  24  24   3   3
scan!

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updated Sun Aug 3 03:27:15 2025