8tiu_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 3' TERMINAL PHOSPHATES. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.90, R-factor=0.200)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tiu_C interface=56,57,58,60,61,64,94,164,165,167,169,170,173,174,200, nsprivqsndlteaayslsrdqkrmlylfvdqirkshdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdit
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.436 IC/col=0.687 n_of_columns=21

specificity:

A |   0   3  24  24   0   0   8  24  24  24  24   0   0   0   0  96   0  71  24  12   7
C |   4   9  24  24   0   0  64  24  24  24  24   0   0   0  96   0  96  11  24  14   8
G |   0  81  24  24  96  96   7  24  24  24  24   0  96   0   0   0   0   7  24  60   7
T |  92   3  24  24   0   0  17  24  24  24  24  96   0  96   0   0   0   7  24  10  74

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updated Fri Sep 13 13:46:56 2024