interface graph thumbnail
legend  pdf

structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.35, R-factor=0.239)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex7rva_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSESKRRSYRPDRRR

Estimated binding specificities ?

readout + contactlogo
# IC=6.236 IC/col=0.208 n_of_columns=30 specificity:   
A |  24  24  24  24  24  45  15  24  16  11   0   0  60   5  70  24  24  24  24  16  15  20  21  22  10  51  18  24  24  24
C |  24  24  24  24  24  19  49  24  16   9   0   0  12  85  10  24  24  24  24  16  49  38  33  25  66  15  18  24  24  24
G |  24  24  24  24  24  16  17  24  16  67   0  96  12   3   8  24  24  24  24  48  17  19  21  22  10  15  42  24  24  24
T |  24  24  24  24  24  16  15  24  48   9  96   0  12   3   8  24  24  24  24  16  15  19  21  27  10  15  18  24  24  24
scan!

home
updated Tue Dec 19 05:01:27 2023