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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.35, R-factor=0.239)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.896 IC/col=0.709 n_of_columns=21 specificity:   
A |  96   2  24   1   0   0   0  96   0  96  24  24  24  24  22  69   0  24  24   0  93
C |   0  69  24  17   0   0   0   0  96   0  24  24  24  24  14  23  96  24  24  96   0
G |   0   5  24  20  96   0  96   0   0   0  24  24  24  24  43   4   0  24  24   0   2
T |   0  20  24  58   0  96   0   0   0   0  24  24  24  24  17   0   0  24  24   0   1
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updated Fri Sep 13 13:47:11 2024