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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.35, R-factor=0.239)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.226 IC/col=0.677 n_of_columns=21 specificity:   
A |  78   1  24   1   0   0   0  84   0  94  24  24  24  24   7  59   3  24  24   1  92
C |   5  87  24  11   0   0   0   6  96   1  24  24  24  24  12  28  92  24  24  90   1
G |   7   3  24   9  96   0  96   3   0   0  24  24  24  24  76   6   0  24  24   4   3
T |   6   5  24  75   0  96   0   3   0   1  24  24  24  24   1   3   1  24  24   1   0
scan!

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updated Sun Aug 3 03:27:31 2025