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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.35, R-factor=0.239)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.712 IC/col=0.701 n_of_columns=21 specificity:   
A |  88   0  24   7   0   0   0  88   0  90  24  24  24  24  10  87   3  24  24   4  93
C |   4  88  24  15   0   0   0   2  96   2  24  24  24  24  12   5  93  24  24  88   0
G |   2   2  24  10  96   0  96   4   0   2  24  24  24  24  72   2   0  24  24   2   3
T |   2   6  24  64   0  96   0   2   0   2  24  24  24  24   2   2   0  24  24   2   0
scan!

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updated Mon Jun 29 11:39:47 2026