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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.201)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.185 IC/col=0.723 n_of_columns=21 specificity:   
A |   0   4  24  24   0   0   4  24  24  24  24   4   0   4   0  96   0  82  24   8   4
C |   5   0  24  24   0   0  84  24  24  24  24   0   0   4  96   0  96   4  24   4   4
G |   0  88  24  24  91  96   4  24  24  24  24   0  96   4   0   0   0   8  24  78   4
T |  91   4  24  24   5   0   4  24  24  24  24  92   0  84   0   0   0   2  24   6  84
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updated Tue Dec 17 20:03:47 2024