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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.201)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.597 IC/col=0.695 n_of_columns=21 specificity:   
A |  74   8  24   8   0   0   0  87   0  96  24  24  24  24   8   0   5  24  24   4  91
C |  10  69  24   8   0   0   0   5  96   0  24  24  24  24   4  96  91  24  24  88   1
G |   4  11  24   6  96   0  96   4   0   0  24  24  24  24  78   0   0  24  24   4   4
T |   8   8  24  74   0  96   0   0   0   0  24  24  24  24   6   0   0  24  24   0   0
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updated Sun Aug 3 03:27:53 2025