8tiw_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.11, R-factor=0.201)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tiw_C interface=54,55,56,58,59,62,92,161,162,164,166,167,170,171,197, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffirftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.798 IC/col=0.705 n_of_columns=21

specificity:

A |   0   6  24  24   0   0   0  24  24  24  24   0   0   4   0  96   0  74  24  10   4
C |   4   4  24  24   1   0  91  24  24  24  24   0   0   6  96   0  96   6  24   4   4
G |   1  82  24  24  91  96   0  24  24  24  24   0  96   4   0   0   0   8  24  69   8
T |  91   4  24  24   4   0   5  24  24  24  24  96   0  82   0   0   0   8  24  13  80

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updated Sat Jan 10 02:14:20 2026