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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH BLUNT ENDS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.201)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex7rva_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=6.144 IC/col=0.198 n_of_columns=31 specificity:   
A |  24  24  24  24  25  15  10  34  22  19  12  18  24  24  24  24   7   6   9   2  96   8  49  24  18  15  24  24  24  24  24
C |  24  24  24  24  27  17  13  22  20  19  12  42  24  24  24  24   4   6  11  88   0  72  17  24  18  17  24  24  24  24  24
G |  24  24  24  24  22  15  63  20  34  38  60  18  24  24  24  24   4  78   9   4   0   8  15  24  42  15  24  24  24  24  24
T |  24  24  24  24  22  49  10  20  20  20  12  18  24  24  24  24  81   6  67   2   0   8  15  24  18  49  24  24  24  24  24
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updated Tue Dec 19 05:01:40 2023