interface graph thumbnail
legend  pdf

structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=2.91, R-factor=0.200)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex7rva_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

readout + contactlogo
# IC=6.970 IC/col=0.232 n_of_columns=30 specificity:   
A |  24  24  24  20  49  18  24  15  10   0   2  81   1  81  24  24  24  24  18  14  18  21  19  14  51  21  24  24  24  24
C |  24  24  24  22  15  42  24  15   8   0   1   7  92   4  24  24  24  24  18  56  42  33  20  54  15  21  24  24  24  24
G |  24  24  24  34  17  18  24  15  70   0  92   4   2   7  24  24  24  24  42  13  18  21  19  14  15  31  24  24  24  24
T |  24  24  24  20  15  18  24  51   8  96   1   4   1   4  24  24  24  24  18  13  18  21  38  14  15  23  24  24  24  24
scan!

home
updated Tue Dec 19 05:01:54 2023