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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.208)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.524 IC/col=0.739 n_of_columns=21 specificity:   
A |  92  12  24  12   0   0   0  96   0  96  24  24  24  24  12   0   0  24   9   3  93
C |   0  64  24  11   0   0   0   0  96   0  24  24  24  24   9  96  96  24  14  86   0
G |   4   6  24   9  96   0  96   0   0   0  24  24  24  24  66   0   0  24   9   4   3
T |   0  14  24  64   0  96   0   0   0   0  24  24  24  24   9   0   0  24  64   3   0
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updated Sun Aug 3 03:28:32 2025