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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.208)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.659 IC/col=0.746 n_of_columns=21 specificity:   
A |   1   2  64  24   0   0  13  24  24  24  24   0   0   0   0  96   0  75  24  11   1
C |   2   8   8  24   0   0  61  24  24  24  24   0   0   0  96   0  96   2  24  11   2
G |   0  81  11  24  96  96  11  24  24  24  24   0  96   0   0   0   0   8  24  69   0
T |  93   5  13  24   0   0  11  24  24  24  24  96   0  96   0   0   0  11  24   5  93
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updated Sat Jan 10 02:15:00 2026