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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.208)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.650 IC/col=0.745 n_of_columns=21 specificity:   
A |  93  14  24  12   0   0   0  96   0  96  24  24  24  24   6   0   0  24   9   3  92
C |   0  64  24   6   0   0   0   0  96   0  24  24  24  24  12  96  96  24   6  86   0
G |   3   6  24  12  96   0  96   0   0   0  24  24  24  24  64   0   0  24  11   4   3
T |   0  12  24  66   0  96   0   0   0   0  24  24  24  24  14   0   0  24  70   3   1
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updated Fri Sep 13 13:47:56 2024