8tiy_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 1 STICKY BASES AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.11, R-factor=0.208)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	7rva_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tiy_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

readout + contact

# IC=7.054 IC/col=0.235 n_of_columns=30

specificity:

A |  24  24  24  24  22  16  13  42  20  18  12  18  24  24  24  24   7   4   0   0  81   9  45  24  18  14  20  24  24  24
C |  24  24  24  24  27  19  13  18  20  18  12  42  24  24  24  24   4   2   0  96   7  67  16  24  18  13  36  24  24  24
G |  24  24  24  24  25  16  57  18  34  42  60  18  24  24  24  24   4  88   0   0   4  11  19  24  42  13  20  24  24  24
T |  24  24  24  24  22  45  13  18  22  18  12  18  24  24  24  24  81   2  96   0   4   9  16  24  18  56  20  24  24  24

scan!

home
updated Tue Dec 19 05:02:07 2023