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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.195)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.740 IC/col=0.702 n_of_columns=21 specificity:   
A |  91   9  24   7   0   0   0  96   0  96  24  24  24  24   9   0   5  24  24  16  92
C |   1  62  24   9   0   0   0   0  96   0  24  24  24  24   4  96  91  24  24  57   0
G |   4  11  24   4  96   0  96   0   0   0  24  24  24  24  79   0   0  24  24  14   4
T |   0  14  24  76   0  96   0   0   0   0  24  24  24  24   4   0   0  24  24   9   0
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updated Sun Aug 3 03:28:52 2025