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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.11, R-factor=0.195)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex7rva_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=7.751 IC/col=0.267 n_of_columns=29 specificity:   
A |  24  24  24  24  21  16  14  38  19  18  11  18  24  24  24  24   7   1   0   0  96   9  49  24  18  17  22  24  24
C |  24  24  24  24  31  16  16  19  19  18   9  42  24  24  24  24   4   2   0  96   0  67  15  24  18  15  30  24  24
G |  24  24  24  24  21  19  52  20  38  42  67  18  24  24  24  24   4  92   0   0   0  11  17  24  42  15  22  24  24
T |  24  24  24  24  23  45  14  19  20  18   9  18  24  24  24  24  81   1  96   0   0   9  15  24  18  49  22  24  24
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updated Tue Dec 19 05:02:20 2023