8tiz_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND NO TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.11, R-factor=0.195)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tiz_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

readout + contact

# IC=14.881 IC/col=0.709 n_of_columns=21

specificity:

A |   0  10  24  24   0   0   5  24  24  24  24   0   0   0   0  96   0  76  24  10   1
C |   5  11  24  24   1   0  80  24  24  24  24   0   0   0  96   0  96  10  24  11   5
G |   0  65  24  24  90  96   6  24  24  24  24   0  96   0   0   0   0   0  24  65   0
T |  91  10  24  24   5   0   5  24  24  24  24  96   0  96   0   0   0  10  24  10  90

scan!

home
updated Tue Dec 17 20:04:46 2024