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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.24, R-factor=0.197)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.975 IC/col=0.761 n_of_columns=21 specificity:   
A |  65   0  24  11   0   0   0  82   0  96  24  24  24  24   8   0   0  24  91   4  91
C |   8  96  24   8   0   0   0   4  96   0  24  24  24  24   6  96  96  24   1  82   0
G |  13   0  24   8  96   0  96   6   0   0  24  24  24  24  74   0   0  24   0   6   5
T |  10   0  24  69   0  96   0   4   0   0  24  24  24  24   8   0   0  24   4   4   0
scan!

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updated Fri Sep 13 13:48:23 2024