8tj0_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.24, R-factor=0.197)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	7rva_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tj0_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

readout + contact

# IC=6.768 IC/col=0.233 n_of_columns=29

specificity:

A |  24  24  24  24  20  15  12  42  20  19  16  18  24  24  24  24   4   1   8   0  93   8  42  24  18  16  22  24  24
C |  24  24  24  24  36  15  12  18  20  16  14  42  24  24  24  24   7   1   8  96   1  72  18  24  18  19  30  24  24
G |  24  24  24  24  20  17  60  18  34  45  52  18  24  24  24  24   4  93  10   0   1   8  18  24  42  16  22  24  24
T |  24  24  24  24  20  49  12  18  22  16  14  18  24  24  24  24  81   1  70   0   1   8  18  24  18  45  22  24  24

scan!

home
updated Tue Dec 19 05:02:33 2023