8tj0_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.24, R-factor=0.197)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tj0_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=16.000 IC/col=0.762 n_of_columns=21

specificity:

A |  64   0  24   8   0   0   0  87   0  96  24  24  24  24  10   0   0  24  91   4  91
C |   8  96  24  10   0   0   0   4  96   0  24  24  24  24   4  96  96  24   0  83   1
G |  12   0  24  12  96   0  96   4   0   0  24  24  24  24  70   0   0  24   1   5   4
T |  12   0  24  66   0  96   0   1   0   0  24  24  24  24  12   0   0  24   4   4   0

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updated Sun Aug 3 03:29:08 2025