8tj0_C : 3D-footprint complex

structure name	ISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 5' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC. (Replication initiation protein)
reference	Slaughter et al.
source	Escherichia coli K-12
experiment	X-ray (resolution=3.24, R-factor=0.197)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tj0_C interface=54,55,56,58,59,62,92,162,163,165,167,168,171,172,198, sprivqsndlteaayslsrdqkrmlylfvdqirksdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyyesfpwfikpahspsRglysvhinpylipffigrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdi
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=15.928 IC/col=0.758 n_of_columns=21

specificity:

A |   0   4   4  24   0   0   8  24  24  24  24   0   0   4   0  96   0  64  24   0   8
C |   4   4   0  24   0   0  68  24  24  24  24   0   0   4  96   0  96   8  24   0  12
G |   0  84   0  24  96  96  12  24  24  24  24   0  96   4   0   0   0  12  24  96  12
T |  92   4  92  24   0   0   8  24  24  24  24  96   0  84   0   0   0  12  24   0  64

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updated Sat Jan 10 02:15:43 2026