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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.207)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.451 IC/col=0.688 n_of_columns=21 specificity:   
A |   0   3  24  24   1   0  10  24  24  24  24   1   0   0   0  96   0  71  24  10   3
C |   4   3  24  24   0   0  69  24  24  24  24   0   0   0  96   0  96  10  24  10   7
G |   0  87  24  24  92  96   3  24  24  24  24   3  96   0   0   0   0   5  24  64  12
T |  92   3  24  24   3   0  14  24  24  24  24  92   0  96   0   0   0  10  24  12  74
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updated Sat Jan 10 02:16:01 2026