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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.207)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.460 IC/col=0.689 n_of_columns=21 specificity:   
A |   0   3  24  24   0   0  12  24  24  24  24   0   0   0   0  96   0  68  24  11   3
C |   4   5  24  24   0   0  68  24  24  24  24   0   0   0  96   0  96  10  24  10  10
G |   0  85  24  24  93  96  10  24  24  24  24   3  96   0   0   0   0  12  24  65   6
T |  92   3  24  24   3   0   6  24  24  24  24  93   0  96   0   0   0   6  24  10  77
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updated Fri Sep 13 13:48:37 2024