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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.207)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=14.684 IC/col=0.699 n_of_columns=21 specificity:   
A |  80   7  24  11   0   0   0  96   0  92  24  24  24  24   9   0   4  24  24   3  96
C |   3  65  24   7   0   0   0   0  96   0  24  24  24  24   7  96  92  24  24  87   0
G |   7  13  24  11  96   0  96   0   0   4  24  24  24  24  69   0   0  24  24   3   0
T |   6  11  24  67   0  96   0   0   0   0  24  24  24  24  11   0   0  24  24   3   0
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updated Tue Dec 17 20:05:23 2024