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structure nameISORETICULAR, INTERPENETRATING CO-CRYSTAL OF REPLICATION INITIATOR PROTEIN REPE54 AND SYMMETRICAL EXPANDED DUPLEX (31MER) CONTAINING THE COGNATE REPE54 SEQUENCE AND AN ADDITIONAL G-C RICH SEQUENCE WITH 2 STICKY BASE OVERHANGS AND 3' TERMINAL PHOSPHATES AND CROSSLINKED WITH EDC.
(Replication initiation protein)
referenceSlaughter et al.
sourceEscherichia coli K-12
experimentX-ray (resolution=3.15, R-factor=0.207)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
reference complex7rva_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=7.191 IC/col=0.248 n_of_columns=29 specificity:   
A |  24  24  24  49  18  24  16   6   0   0  78   1  74  24  24  24  24  18  13  20  20  19  12  49  20  24  24  24  24
C |  24  24  24  15  42  24  19   6   0   0   6  92   7  24  24  24  24  18  63  38  36  19  60  15  19  24  24  24  24
G |  24  24  24  17  18  24  16  78   0  96   6   2   7  24  24  24  24  42  10  19  20  20  12  17  38  24  24  24  24
T |  24  24  24  15  18  24  45   6  96   0   6   1   8  24  24  24  24  18  10  19  20  38  12  15  19  24  24  24  24
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updated Tue Dec 19 05:02:45 2023