8tkl_AB : 3D-footprint complex

structure name	MURINE NF-KAPPAB P50 REL HOMOLOGY REGION HOMODIMER IN COMPLEX WITH A TEST 16-MER KAPPAB-LIKE DNA
reference	Rogers et al. Biomolecules 13 ? 2023
source	Mus musculus
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1nfk_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tkl_A interface=16,18,19,21,22,26,203,234,267, gpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdKvqkddiqirfyeeeenggvwegfgdfsptdvhRqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype > 8tkl_B interface=16,18,19,21,22,26,203, gpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCEHKKR/RRYCEHK

Estimated binding specificities ?

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# IC=11.096 IC/col=1.009 n_of_columns=11

specificity:

A |   0   0   0   0  54  24  13   0   0   0   0
C |   0   0   0   0  13  24  16   0  96  96  96
G |  96  96  96  96  16  24  13   0   0   0   0
T |   0   0   0   0  13  24  54  96   0   0   0

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updated Fri Aug 1 18:24:46 2025