8tkm_AB : 3D-footprint complex

structure name	MURINE NF-KAPPAB P50 REL HOMOLOGY REGION HOMODIMER IN COMPLEX WITH 17- MER KAPPAB DNA FROM HUMAN INTERLEUKIN-6 (IL-6) PROMOTER
reference	Rogers et al. Biomolecules 13 ? 2023
source	Mus musculus
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1nfk_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tkm_A interface=16,18,19,21,22,25,26,203, gpylqileqpkqrgfRfRYvCEgpSHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype > 8tkm_B interface=16,18,19,21,22,26,203, gpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCESHK/RRYCEHK

Estimated binding specificities ?

readout + contact

# IC=10.999 IC/col=1.000 n_of_columns=11

specificity:

A |   0   0   0  96  48  24  12   0   0   0   0
C |   0   0   0   0  12  24  24   0  96  96  96
G |  96  96  96   0  12  24  12   0   0   0   0
T |   0   0   0   0  24  24  48  96   0   0   0

scan!

home
updated Fri Aug 1 18:25:03 2025