8tkm_AB : 3D-footprint complex

structure name	MURINE NF-KAPPAB P50 REL HOMOLOGY REGION HOMODIMER IN COMPLEX WITH 17- MER KAPPAB DNA FROM HUMAN INTERLEUKIN-6 (IL-6) PROMOTER
reference	Rogers et al. Biomolecules 13 ? 2023
source	Mus musculus
experiment	X-ray (resolution=2.80, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8tkm_A interface=16,18,19,21,22,25,26,203, gpylqileqpkqrgfRfRYvCEgpSHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype > 8tkm_B interface=16,18,19,21,22,26,203, gpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCESHK/RRYCEHK

Estimated binding specificities ?

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# IC=10.981 IC/col=0.998 n_of_columns=11

specificity:

A |   0   0   0  96  54  24  13   0   0   0   0
C |   0   0   0   0  13  24  15   0  96  96  96
G |  96  96  96   0  13  24  27   0   0   0   0
T |   0   0   0   0  16  24  41  96   0   0   0

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updated Mon Dec 16 11:28:30 2024