1dsz_AB : 3D-footprint complex

structure name	STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
reference	Khorasanizadeh et al. 'EMBO 19 1045 2000
source	HOMO SAPIENS
experiment	X-ray (resolution=1.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1dsz_A 6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1dsz_A interface=20,23,27,28, pcfvcqdkssgyhygvsacEgcKgffRRsiqknmvytchrdknciinkvtrnrcqycrlqkcfevgmskesvrnd > 1dsz_B interface=26,29,33,34,82, gsftkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeRqr
interface signature	EKRR/EKKRR

Estimated binding specificities ?

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# IC=10.546 IC/col=0.879 n_of_columns=12

specificity:

A |  11   0  88   0   0  24  24   8   0  69   0   0
C |   8   0   0  96  96  24  24   8   0   8  96  96
G |   8  96   8   0   0  24  24   8  96  11   0   0
T |  69   0   0   0   0  24  24  72   0   8   0   0

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updated Wed Jun 24 09:02:27 2026