1dsz_AB : 3D-footprint complex

structure name	STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
reference	Khorasanizadeh et al. 'EMBO 19 1045 2000
source	HOMO SAPIENS
experiment	X-ray (resolution=1.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1dsz_A 6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1dsz_A interface=20,23,27,28, pcfvcqdkssgyhygvsacEgcKgffRRsiqknmvytchrdknciinkvtrnrcqycrlqkcfevgmskesvrnd > 1dsz_B interface=26,29,33,34,82, gsftkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeRqr
interface signature	EKRR/EKKRR

Estimated binding specificities ?

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# IC=11.563 IC/col=0.964 n_of_columns=12

specificity:

A |   0   0   7   0  82  24   7   0   0   0   0  68
C |   0   0   1  96   7  24   9   0   0   7  96   7
G |  96  96   7   0   0  24  66  96  96   1   0  14
T |   0   0  81   0   7  24  14   0   0  88   0   7

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updated Mon Sep 9 12:05:10 2024