1dsz_AB : 3D-footprint complex

structure name	STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
reference	Khorasanizadeh et al. 'EMBO 19 1045 2000
source	HOMO SAPIENS
experiment	X-ray (resolution=1.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1dsz_A 6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1dsz_A interface=20,23,27,28, pcfvcqdkssgyhygvsacEgcKgffRRsiqknmvytchrdknciinkvtrnrcqycrlqkcfevgmskesvrnd > 1dsz_B interface=26,29,33,34,82, gsftkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeRqr
interface signature	EKRR/EKKRR

Estimated binding specificities ?

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# IC=11.507 IC/col=0.959 n_of_columns=12

specificity:

A |   0   0   6   0  83  24  12   0   0   0   0  70
C |   0   0   6  96   6  24   8   0   0   7  96  14
G |  96  96   6   0   1  24  64  96  96   0   0   6
T |   0   0  78   0   6  24  12   0   0  89   0   6

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updated Tue Jul 29 14:32:20 2025