interface graph thumbnail
legend  pdf

structure nameTWO HUMAN C-FOS:C-JUN:DNA COMPLEXES
(C-JUN PROTO-ONCOGENE PROTEIN)
referenceGlover et al. Nature 373 257 1995
sourceHOMO SAPIENS
experimentX-ray (resolution=3.05, R-factor=0.230)
structural superfamilyLeucine zipper domain;A DNA-binding domain in eukaryotic transcription factors;
sequence familybZIP transcription factor; Basic region leucine zipper;
multimeric complexes1a02_FJN 1fos_EF 1fos_GH 1jnm_AB 1s9k_CDE 2h7h_AB 5t01_AB
reference complex5t01_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNAASR

Estimated binding specificities ?

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# IC=4.516 IC/col=0.903 n_of_columns=5 specificity:   
A |  96   0   0  13  57
C |   0   0   0  57  13
G |   0  96   0  13  13
T |   0   0  96  13  13
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updated Sat Aug 2 00:53:09 2025