1le5_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A NF-KB HETERODIMER BOUND TO AN IFNB-KB
reference	Chen-Park et al. J.Biol.Chem. 277 24694 2002
source	MUS MUSCULUS
experiment	X-ray (resolution=2.75, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1nfk_A 9bdw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1le5_A interface=16,18,19,21,22,26,170, mayveiieqpkqrgmRfRYkCEgrsAgsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpd > 1le5_B interface=17,20,23,27,204,206,235, mgpylqileqpkqrgfRfrYvcEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKaPnasnlkivrmdrtagcvtggeeiyllcdKvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCEAR/RYEHKPK

Estimated binding specificities ?

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# IC=11.397 IC/col=1.036 n_of_columns=11

specificity:

A |   0   0   0  84  96  78   6   0   0   0  78
C |   0   6   0   6   0   6   6   0  96  84   6
G |  96  84  96   6   0   6   6   0   0   6   6
T |   0   6   0   0   0   6  78  96   0   6   6

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updated Mon Sep 9 12:47:34 2024