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structure nameNF-KAPPAB RELA HOMO-DIMER BOUND TO GC-CENTRIC KAPPAB DNA
(Transcription factor p65)
referenceTsodikov et al. Proc.Natl.Acad.Sci.USA 121 e2405555121 2024
sourceMus musculus
experimentX-ray (resolution=1.87, R-factor=0.157)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1le5_AB 1le5_EF 1le9_AB 1le9_EF 1lei_AB 1ram_AB 1vkx_AB 2i9t_AB 2ram_AB 3gut_ABD 3gut_CF 3gut_EGH 5u01_ABCD 9bdu_AB 9bdv_AB 9bdw_AB 9bdx_AB
redundant complexes1le5_A 1le9_A 1ram_B 1vkx_A 2ram_B 5u01_A 9bdu_A 9bdv_A 9bdx_A 1lei 2i9t 3gut
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRYCERR

Estimated binding specificities ?

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# IC=5.937 IC/col=0.990 n_of_columns=6 specificity:   
A |   0  16   0   0  80  48
C |   0   0   0   0   0  16
G |   0  80  96  96  16  16
T |  96   0   0   0   0  16
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updated Mon Aug 4 02:46:58 2025