1le5_EF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A NF-KB HETERODIMER BOUND TO AN IFNB-KB
reference	Chen-Park et al. J.Biol.Chem. 277 24694 2002
source	MUS MUSCULUS
experiment	X-ray (resolution=2.75, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1nfk_A 9bdw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1le5_E interface=16,18,19,21,22,170,229, mayveiieqpkqrgmRfRYkCEgrsagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhRqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpd > 1le5_F interface=17,19,20,22,23,27,204,235, mgpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdKvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCERR/RRYCEHKK

Estimated binding specificities ?

readout + contact

# IC=9.764 IC/col=0.976 n_of_columns=10

specificity:

A |   0   0   0  96  54  24  13   0   0   0
C |   0   0   0   0  13  24  16   0  96  96
G |  96  96  96   0  13  24  13   0   0   0
T |   0   0   0   0  16  24  54  96   0   0

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updated Tue Jul 29 15:17:30 2025