interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF C/EBPALPHA-DNA COMPLEX
(CCAATenhancer binding protein alpha)
referenceSebastian et al. J.Biol.Chem. 278 15178 2003
sourceRattus norvegicus
experimentX-ray (resolution=2.80, R-factor=0.221)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper;
multimeric complexes1nwq_AC
reference complex8k8c_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNNAVR

Estimated binding specificities ?

readout + contactlogo
# IC=4.381 IC/col=0.876 n_of_columns=5 specificity:   
A |  21   0   0  96  55
C |  44   0  96   0  21
G |  21  96   0   0  10
T |  10   0   0   0  10
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: EBPALPHA
TTGCGTCATPubMed1nwq_A(2.91e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ------RA----NANCATAT--STRG   L        +-2e42_B    
                                      +-5 
  ------RC----NANCAAVT----RG   L      ! ! +1nwq_A    
                                   +--7 +-1 
  RGQGNART--AGQT--FTRG------   L   !  !   +1gd2_F    
                                   !  ! 
  ------NCRT--ATAT--STRG----   L   !  +--1t2k_D    
                                   ! 
  ------------NT--ATAT--STRC   L --8       +1jnm_A    
                                   !     +-3 
  ------------NCRTATAT--STRG   L   !   +-4 +1dh3_A    
                                   !   ! ! 
  ------------NC--AAAT----RT   L   +---6 +1a02_F    
                                       ! 
  ------------NCTT--AT----RG   L       ! +2dgc_A    
                                       +-2 
  ------------NT--ATAT--STRA   L         +2c9l_Y    
                                 

home
updated Thu Sep 12 15:03:02 2024