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structure nameCRYSTAL STRUCTURE OF C/EBPALPHA-DNA COMPLEX
(CCAATenhancer binding protein alpha)
referenceSebastian et al. J.Biol.Chem. 278 15178 2003
sourceRattus norvegicus
experimentX-ray (resolution=2.80, R-factor=0.221)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper;
multimeric complexes1nwq_AC 8k8c_AB
reference complex8k8c_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNNAVR

Estimated binding specificities ?

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# IC=4.349 IC/col=0.870 n_of_columns=5 specificity:   
A |  23   0   0  96  53
C |  42   0  96   0  23
G |  21  96   0   0  10
T |  10   0   0   0  10
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: EBPALPHA
TTGCGTCATPubMed1nwq_A(2.91e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ------RA----NANCATAT--STRG   L        +-2e42_B    
                                      +-5 
  ------RC----NANCAAVT----RG   L      ! ! +1nwq_A    
                                   +--7 +-1 
  RGQGNART--AGQT--FTRG------   L   !  !   +1gd2_F    
                                   !  ! 
  ------NCRT--ATAT--STRG----   L   !  +--1t2k_D    
                                   ! 
  ------------NT--ATAT--STRC   L --8       +1jnm_A    
                                   !     +-3 
  ------------NCRTATAT--STRG   L   !   +-4 +1dh3_A    
                                   !   ! ! 
  ------------NC--AAAT----RT   L   +---6 +1a02_F    
                                       ! 
  ------------NCTT--AT----RG   L       ! +2dgc_A    
                                       +-2 
  ------------NT--ATAT--STRA   L         +2c9l_Y    
                                 

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updated Mon Dec 16 18:17:49 2024