interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD3-MH1 BOUND TO DNA AT 2.4 A RESOLUTION
(SMAD 3)
referencePavletich et al. J.Biol.Chem. 278 20327 2003
sourceHomo sapiens
experimentX-ray (resolution=2.40, R-factor=?)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
redundant complexes1mhd
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQK

Estimated binding specificities ?

contactlogo
# IC=2.160 IC/col=0.540 n_of_columns=4 specificity:   
A |  76   7  42   5
C |   5   7  18  82
G |  11  76  18   5
T |   4   6  18   4
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: SMAD3
CAGACAPubMed1ozj_B(4.36e-07), 1mhd_AB(8.98e-05), 1ozj_AB(4.24e-05), ... (total=4)
GTCTAGACPubMed1ozj_B(1.77e-03), 1mhd_AB(1.05e-12), 1ozj_AB(1.10e-13), ... (total=4)
TGCCAGACAPubMed1ozj_B(1.09e-05), 1mhd_AB(4.94e-04), 1ozj_AB(1.73e-04), ... (total=4)
TGTGTATTPubMed1mhd_AB(8.27e-03), 1ozj_AB(6.90e-03)

home
updated Mon Dec 16 18:21:03 2024