1vkx_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
reference	Huang et al.
source	MUS MUSCULUS
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1nfk_A 9bdw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1vkx_A interface=15,17,18,20,21,169, ayveiieqpkqrgmRfRYkCEgrsagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpd > 1vkx_B interface=16,18,19,21,22,26,203, gpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCER/RRYCEHK

Estimated binding specificities ?

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# IC=10.656 IC/col=0.969 n_of_columns=11

specificity:

A |  21   0   0   0  67   0  24   9   0   0   0
C |   9   0   0   0  29  96  24  21   0  96  96
G |   9  96  96  96   0   0  24   9   0   0   0
T |  57   0   0   0   0   0  24  57  96   0   0

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updated Tue Jul 29 17:00:22 2025