1vkx_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
reference	Huang et al.
source	MUS MUSCULUS
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	9bdw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1vkx_A interface=15,17,18,20,21,169, ayveiieqpkqrgmRfRYkCEgrsagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpd > 1vkx_B interface=16,18,19,21,22,26,203, gpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCER/RRYCEHK

Estimated binding specificities ?

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# IC=10.754 IC/col=0.978 n_of_columns=11

specificity:

A |  24   0   0   0  72   0  24  12   0   0   0
C |  12   0   0   0  24  96  24  24   0  96  96
G |   0  96  96  96   0   0  24  12   0   0   0
T |  60   0   0   0   0   0  24  48  96   0   0

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updated Fri Dec 13 11:25:56 2024