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legend  pdf

structure nameCRYSTAL STRUCTURE OF A LAMBDA INTEGRASE(75-356) DIMER BOUND TO A COC' CORE SITE
referenceRadman-Livaja et al. Nature 435 1059 2005
sourceENTEROBACTERIA PHAGE LAMBDA
experimentX-ray (resolution=2.80, R-factor=0.218)
structural superfamilyDNA breaking-rejoining enzymes;
sequence familyPhage integrase family; Phage integrase, Nterminal SAMlike;
multimeric complexes5j0n_EKLMNO 5j0n_FIJ
redundant complexes1p7d 1z1g 1z1b 2wcc
reference complex2wcc_3
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTNYSASLKSRYM

Estimated binding specificities ?

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# IC=8.957 IC/col=0.896 n_of_columns=10 specificity:   
A |   0  24   7   0  73   7   0   0   0  73
C |   0  24  75  96   7   9  96   0   0   9
G |   0  24   7   0   9   7   0   0   0   7
T |  96  24   7   0   7  73   0  96  96   7
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: LAMBDA INTEGRASE
GAAAAPubMed2wcc_3(2.92e-03)
CAACTTNNTPubMed1z19_A(7.53e-03)
CACGTGACPubMed1z1b_B(1.78e-03)

Dendrogram of similar interfaces ?

matrix format
  
  --KGTA--NAYTSA------ATST----LT----------KA--------STRGYT----   L                   +----------1z19_A    
                                                                                   +-1 
  KTKATT--AAYCHTWTHTKT----KGTT----LTNC--------NCTC--QGKG------   L         +-------2 +----------2a3v_B    
                                                                           !       ! 
  --HTTTKGMT--ST--------KATT----QT--QT--------STRG--EA--------   L   +-----3       +-----------1xo0_B    
                                                                     !     ! 
  ----------------------------------------KA--------RG----NAKA     --4     +-------------------1p4e_A    
                                                                     ! 
  ------------------------------------RGKA--RG----AATG----NT--   L   +-------------------------2v6e_B    
                                                                   

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updated Thu Jan 8 19:30:33 2026