2i9t_AB : 3D-footprint complex

structure name	STRUCTURE OF NF-KB P65-P50 HETERODIMER BOUND TO PRDII ELEMENT OF B- INTERFERON PROMOTER
reference	Escalante et al. Structure 10 383 2002
source	MUS MUSCULUS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1nfk_A 9bdw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2i9t_A interface=17,19,20,22,23,26,171, hapyveiieqpkqrgmRfRYkCEgrSagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpd > 2i9t_B interface=16,18,19,21,22,25,26,203, gpylqileqpkqrgfRfRYvCEgpSHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCESR/RRYCESHK

Estimated binding specificities ?

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# IC=6.725 IC/col=0.672 n_of_columns=10

specificity:

A |   1   0  62  39  24   9  12   2   0   5
C |   2   0  12  19  24  10  12  91  95  81
G |  92  95   9  19  24   8  14   2   0   7
T |   1   1  13  19  24  69  58   1   1   3

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updated Mon Sep 9 15:13:10 2024