2i9t_AB : 3D-footprint complex

structure name	STRUCTURE OF NF-KB P65-P50 HETERODIMER BOUND TO PRDII ELEMENT OF B- INTERFERON PROMOTER
reference	Escalante et al. Structure 10 383 2002
source	MUS MUSCULUS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	9bdw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2i9t_A interface=17,19,20,22,23,26,171, hapyveiieqpkqrgmRfRYkCEgrSagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgyyeadlcpdrsihsfqnlgiqcvkkrdleqaisqriqtnnnpfhvpieeqrgdydlnavrlcfqvtvrdpagrpllltpvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdkvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpd > 2i9t_B interface=16,18,19,21,22,25,26,203, gpylqileqpkqrgfRfRYvCEgpSHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydsKapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCESR/RRYCESHK

Estimated binding specificities ?

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# IC=6.717 IC/col=0.672 n_of_columns=10

specificity:

A |   3   0   2  58  67  24  20  12   0   2
C |   6   0   1  12  10  24  19  10  96  91
G |  81  96  91  12  10  24  19  13   0   2
T |   6   0   2  14   9  24  38  61   0   1

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updated Fri Dec 13 12:16:02 2024