2jlg_B : 3D-footprint complex

structure name	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE (RNA-DIRECTED RNA POLYMERASE)
reference	Koivunen et al. 'Nucleic 36 6633 2008
source	PSEUDOMONAS PHAGE PHI6
experiment	X-ray (resolution=2.80, R-factor=0.220)
structural superfamily	DNA/RNA polymerases;
sequence family	RNA dependent RNA polymerase;
redundant complexes	1hht_R 4a8s_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2jlg_B interface=26,30,144,202,204,272,288,291,393,398,530,543,628,629,633,634,642, prrapafplsdikaqmlfannikaqQaskRsfkegaietyegllsvdprflsfknelsryltdhfpanvdeygrvygngvrtnffgmrhmngfpmipatwplasnlkkradadladgpvserdnllfraavrlmfsdlepvplKirkgsstcipyfsndmgtkieiaeralekaeeagnlmlqgkfddayqlhqmggayyvVyRaqstdaitldpktgkfvskdrmvadfeyavtggeqgslfaaskdasrlkeqygidvpdgffcerrrtAmggpfalnapimavaQpvRnkiyskyaytfhhttrlnkeekvkewslcvatdvsdhdtfwpgwlrdlicdellnmgyapwwvklfetslklpvyvgapapeqghtllgdpsnpdlevglsSgqgaTdlmgtllmsitylvmqldhtaphlnsrikdmpsacrfldsywqgheeirqisksddamlgwtkgralvgghrlfemlkegkvnpspymkisyqhggaflgdillydsrrepgsaifvgninsmlnnqfspeYgvqsgvrdrskrKrpfpglawasmkdtygacpiysdvleaiercwwnafgesyrayredmlkrdtlelsryvasmarqaglaeltpidlevladpnkLQykwTEadvsaniHevlmhgvsvekterflrsvmpr
interface signature	QRKVRAQRSTYKLQTEH

Estimated binding specificities ?

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# IC=4.489 IC/col=0.898 n_of_columns=5

specificity:

A |  19   9   0   0   0
C |  19   9   0  96  96
G |  19  11   0   0   0
T |  39  67  96   0   0

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Dendrogram of similar interfaces ?

matrix format

  
  QTRTKCVTRT----AT--QCRC--STTC--------YTKTLCQCTCECHC   L           +--------------------2jlg_B    
                                                             +-----1 
  ----------------------------YA--------------------       +-2     +--------------------6ar1_A    
                                                           ! ! 
  ------------------------------KGLGKG--------------   L --3 +--------------------------6me0_C    
                                                           ! 
  ----------LCIC--FA----YG--------------------------       +---------------------------7kqn_D

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updated Tue Dec 17 22:53:10 2024