2nll_AB : 3D-footprint complex

structure name	RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
reference	Rastinejad et al. Nature 375 203 1995
source	HOMO SAPIENS
experiment	X-ray (resolution=1.90, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	2nll_B 6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2nll_A interface=19,22,26,27, caicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgm > 2nll_B interface=22,25,29,30,85, delcvvcgdkatgyhyrcitcEgcKgffRRtiqknlhpsysckyegkcvidkvtrnqcqecrfkkciyvgmatdlvlddskrlaKrklieenrekrrreelek
interface signature	EKKR/EKRRK

Estimated binding specificities ?

readout + contact

# IC=9.335 IC/col=0.622 n_of_columns=15

specificity:

A |  13   0  96   0   0  13  24  24  24  24   4  24  59   9   0
C |  16   0   0  96  96  20  24  24  24  24   4  24   9  86  96
G |  13  96   0   0   0   9  24  24  24  24   4  24  24   1   0
T |  54   0   0   0   0  54  24  24  24  24  84  24   4   0   0

scan!

home
updated Mon Jan 5 01:01:42 2026