2nll_AB : 3D-footprint complex

structure name	RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
reference	Rastinejad et al. Nature 375 203 1995
source	HOMO SAPIENS
experiment	X-ray (resolution=1.90, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	2nll_B 6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2nll_A interface=19,22,26,27, caicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgm > 2nll_B interface=22,25,29,30,85, delcvvcgdkatgyhyrcitcEgcKgffRRtiqknlhpsysckyegkcvidkvtrnqcqecrfkkciyvgmatdlvlddskrlaKrklieenrekrrreelek
interface signature	EKKR/EKRRK

Estimated binding specificities ?

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# IC=9.413 IC/col=0.628 n_of_columns=15

specificity:

A |  15   0  96   0   0  11  24  24  24  24   6  24  65  10   0
C |  10   0   0  96  96  10  24  24  24  24   5  24  10  85  96
G |  11  96   0   0   0  15  24  24  24  24   5  24  16   0   0
T |  60   0   0   0   0  60  24  24  24  24  80  24   5   1   0

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updated Wed Jun 24 13:03:25 2026