2nll_AB : 3D-footprint complex

structure name	RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
reference	Rastinejad et al. Nature 375 203 1995
source	HOMO SAPIENS
experiment	X-ray (resolution=1.90, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	2nll_B 6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2nll_A interface=19,22,26,27, caicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgm > 2nll_B interface=22,25,29,30,85, delcvvcgdkatgyhyrcitcEgcKgffRRtiqknlhpsysckyegkcvidkvtrnqcqecrfkkciyvgmatdlvlddskrlaKrklieenrekrrreelek
interface signature	EKKR/EKRRK

Estimated binding specificities ?

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# IC=8.305 IC/col=0.554 n_of_columns=15

specificity:

A |   0   0  16  24  73  24  24  24  24  24   0   0   0   0  67
C |   0   0  16  24  11  24  24  24  24  24   0   0   7  96  11
G |  96  73  11  24   7  24  24  24  24  24  96  96   5   0  16
T |   0  23  53  24   5  24  24  24  24  24   0   0  84   0   2

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updated Tue Jul 29 18:02:33 2025