| structure name | RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA (PROTEIN THYROID HORMONE RECEPTOR) |
| reference | Rastinejad et al. Nature 375 203 1995 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=1.90, R-factor=0.206) |
| structural superfamily | Glucocorticoid receptor-like DNA-binding domain; |
| sequence family | Zinc finger, C4 type two domains; |
| multimeric complexes | 2nll_AB 3m9e_AB 3m9e_EF |
| redundant complexes |  3m9e_B
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | EKRRK |
Estimated binding specificities ?
| readout + contact |  |
A | 19 10 67 0 5 C | 20 8 12 95 79 G | 19 68 10 0 5 T | 38 10 7 1 7scan! |
Dendrogram of similar interfaces ?
matrix format----EA--KG--RTRG------ L +-----1kb2_B +--10 ----EC--KG--KTRG------ L ! +-----2nll_A +--11 --HGECAGKGAAKGRT------ L ! ! +---1lo1_A ! ! ! ----EC--KG--KGRG------ L ! +-----8 +1ynw_B ! ! +-5 --------KGVT--RG------ L ! +--6 +5cbz_E +----13 ! ----EC--KG--RGRG--FT-- L ! ! +3dzy_D ! ! ----EA--KG--RTRTRT---- ! ! +4umm_E ! ! +---------1 ----EA--KG--RTRTRT---- ! ! ! +2han_B ! +--12 CA--EC--KG--KGRG----RT L ! ! +---6l6q_B ! ! ! ----DG--KG--RTRG------ L -14 +-----9 +3cbb_A ! ! +-2 ----EC--KG--KGRG------ L ! ! ! +2ff0_A ! +-7 --------KAVA--RA------ L ! ! +5e69_A ! ! +-3 ----EC--KG--KGRG------ ! +-4 +3dzy_A ! ! ----ET--KGAT--RG------ L ! +1lat_A ! --------KGVT--RG------ +-------------------5emp_A |
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updated Tue Dec 17 22:57:08 2024