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legend  pdf

structure nameCRYSTAL STRUCTURE OF PI INITIATOR PROTEIN IN COMPLEX WITH ITERON DNA
(PI protein)
referenceSwan et al. Proc.Natl.Acad.Sci.Usa 103 18481 2006
sourceEscherichia coli
experimentX-ray (resolution=3.10, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTSLYRYPIRDK

Estimated binding specificities ?

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# IC=7.872 IC/col=0.525 n_of_columns=15 specificity:   
A |   0  96  65  87  24  24  24  24  24   4   0  24   4   8   5
C |   0   0   2   2  24  24  24  24  24   2   0  24  71  10  10
G |  96   0  29   5  24  24  24  24  24  27   0  24  13  68   2
T |   0   0   0   2  24  24  24  24  24  63  96  24   8  10  79
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----TT--SGLTYART------YT--PCITRGDCKT--   L                          +-----2nra_C    
                                                 +--------------------1 
  ------SGAAECSAKGRGRGSTYGRTPGDCRGRG--RC   L   +-2                    +-----7rva_C    
                                               ! ! 
  QA------------------------------------     --3 +--------------------------7k63_U    
                                               ! 
  --RC----------------------------------       +---------------------------6l9z_S    
                                             

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updated Mon Jun 29 15:25:59 2026