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structure nameUPDATED CRYSTAL STRUCTURE OF REPLICATION INITIATOR PROTEIN REPE54.
(REPLICATION INITIATION PROTEIN)
referenceWard et al.
sourceESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12)
experimentX-ray (resolution=1.89, R-factor=0.210)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInitiator Replication protein;
multimeric complexes2z9o_AB
redundant complexes1rep 2z9o 7sdp 7sgc 7soz 7spm 7u6k 7u7o 7ufx 7uog 7ur0 7uv6 7uv7 7uxy 8d86 8d8m 8tip 8tiq 8tir 8tis 8tit 8tiu 8tiv 8tiw 8tix 8tiy 8tiz 8tj0 8tj1
reference complex8ac8_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSAESKRRSYRPDRRR

Estimated binding specificities ?

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# IC=16.488 IC/col=0.824 n_of_columns=20 specificity:   
A |   0  24   0   0   0   0  96   0  96  24  24  24  24  12   0   0   8  16   5  90
C |  79  24   0   0   0   0   0  96   0  24  24  24  24   0  96  96  67   5  79   1
G |   1  24   0  96   0  96   0   0   0  24  24  24  24  84   0   0  16  11   7   5
T |  16  24  96   0  96   0   0   0   0  24  24  24  24   0   0   0   5  64   5   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --SGAAECSAKGRG------RG--STYGRTPGDCRGRGRC   L            +-------------------7rva_C    
                                                     +----2 
  ----RTTCDTSCSGKG--RT--------------------   L     +-3    +-------------------5x5l_H    
                                                   ! ! 
  ----------------YG----------------------       +-4 +------------------------2heo_D    
                                                 ! ! 
  DCSA--TATT----RT------RA----------------   L   ! !                         +1z9c_A    
                                               --5 +-------------------------1 
  TT--PTTCSTNT----------RT----------------   L   !                           +4lln_I    
                                                 ! 
  ----RGRGYC------------------------------   L   +---------------------------1cf7_A    
                                               

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updated Fri Sep 13 07:34:18 2024