2o61_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF NFKB, IRF7, IRF3 BOUND TO THE INTERFERON-B ENHANCER
reference	'Cell(Cambridge,Mass.)' 129 1111 2007
source	HOMO SAPIENS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;"Winged helix" DNA-binding domain;
reference complex	1nfk_A 2o61_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o61_A interface=15,17,18,20,21,23,169,200,312,356,357,359,360,363,364,427,429,465,466,468,469,473, gyveiieqpkqrgmRfRYkCEgRsagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgfyeaelcpdrcihsfqnlgiqcvkkrdleqaisqriqtnnnpfqvpieeqrgdydlnavrlcfqvtvrdpsgrplrlppvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdKvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpdaaprvlfgewllgeissgcyeglqwldeartcfrvpwkHfarkdlseadarifkawavargrwppssrpppeaetaeragwkTNfRCalRStrrfvmlrdnsgdpadqhkvyalsgslssdslpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvn > 2o61_B interface=18,20,21,23,24,28, mdgpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgictvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhpdlaylqaegggdrqlgdrekelirqaalqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdinitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCERRKHTNRCRSHLRNRSR/RRYCEH

Estimated binding specificities ?

readout + contact

# IC=24.626 IC/col=0.849 n_of_columns=29

specificity:

A |   2  24  24   0  10  88   0  85  24  24   1   2  85  96  24  24   5   0   0   0  96  87  24   4   0   0   0   0   5
C |  90  24  24   0   7   2   0   5  24  24   0   4   2   0  24  24   6   0   0   0   0   2  24   2   0  96  96   0  80
G |   2  24  24  96  72   2  96   4  24  24   2   2   5   0  24  24   5  96  96  96   0   2  24   2   0   0   0   0   6
T |   2  24  24   0   7   4   0   2  24  24  93  88   4   0  24  24  80   0   0   0   0   5  24  88  96   0   0  96   5

scan!

home
updated Tue Jul 29 18:21:50 2025