2o61_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF NFKB, IRF7, IRF3 BOUND TO THE INTERFERON-B ENHANCER
reference	'Cell(Cambridge,Mass.)' 129 1111 2007
source	HOMO SAPIENS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;"Winged helix" DNA-binding domain;
reference complex	1nfk_A 2pi0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o61_A interface=15,17,18,20,21,23,169,200,312,356,357,359,360,363,364,427,429,465,466,468,469,473, gyveiieqpkqrgmRfRYkCEgRsagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgfyeaelcpdrcihsfqnlgiqcvkkrdleqaisqriqtnnnpfqvpieeqrgdydlnavrlcfqvtvrdpsgrplrlppvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdKvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpdaaprvlfgewllgeissgcyeglqwldeartcfrvpwkHfarkdlseadarifkawavargrwppssrpppeaetaeragwkTNfRCalRStrrfvmlrdnsgdpadqhkvyalsgslssdslpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvn > 2o61_B interface=18,20,21,23,24,28, mdgpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgictvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhpdlaylqaegggdrqlgdrekelirqaalqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdinitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCERRKHTNRCRSHLRNRSR/RRYCEH

Estimated binding specificities ?

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# IC=24.430 IC/col=0.842 n_of_columns=29

specificity:

A |   5  24  24   0  10  92   0  80  24  24   0   4  88  96  24  24   5   0   0   0  96  87  24   2   0   0   0   0   5
C |  90  24  24   0  10   0   0   5  24  24   2   2   2   0  24  24   4   0   0   0   0   2  24   4   0  96  96   0  80
G |   0  24  24  96  66   2  96   6  24  24   4   5   2   0  24  24   7  96  96  96   0   2  24   2   0   0   0   0   6
T |   1  24  24   0  10   2   0   5  24  24  90  85   4   0  24  24  80   0   0   0   0   5  24  88  96   0   0  96   5

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updated Wed Jun 24 13:23:46 2026