2o61_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF NFKB, IRF7, IRF3 BOUND TO THE INTERFERON-B ENHANCER
reference	'Cell(Cambridge,Mass.)' 129 1111 2007
source	HOMO SAPIENS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;"Winged helix" DNA-binding domain;
reference complex	2o61_B 2pi0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o61_A interface=15,17,18,20,21,23,169,200,312,356,357,359,360,363,364,427,429,465,466,468,469,473, gyveiieqpkqrgmRfRYkCEgRsagsipgerstdttkthptikingytgpgtvrislvtkdpphrphphelvgkdcrdgfyeaelcpdrcihsfqnlgiqcvkkrdleqaisqriqtnnnpfqvpieeqrgdydlnavrlcfqvtvrdpsgrplrlppvlshpifdnRapntaelkicrvnrnsgsclggdeifllcdKvqkedievyftgpgweargsfsqadvhrqvaivfrtppyadpslqapvrvsmqlrrpsdrelsepmefqylpdaaprvlfgewllgeissgcyeglqwldeartcfrvpwkHfarkdlseadarifkawavargrwppssrpppeaetaeragwkTNfRCalRStrrfvmlrdnsgdpadqhkvyalsgslssdslpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvn > 2o61_B interface=18,20,21,23,24,28, mdgpylqileqpkqrgfRfRYvCEgpsHgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhcedgictvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhpdlaylqaegggdrqlgdrekelirqaalqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdinitkpasvfvqlrrksdletsepkpflyype
interface signature	RRYCERRKHTNRCRSHLRNRSR/RRYCEH

Estimated binding specificities ?

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# IC=25.420 IC/col=0.877 n_of_columns=29

specificity:

A |   8  96   0   0  96  88  24   8   0   0   0   0  84   7  24   0   6  88  90  24  24  11   0   0   6   0  24  24   4
C |   5   0   0   0   0   3  24   3   0  96  96  96   3  71  24   0   1   3   4  24  24  13  96   0  84  96  24  24   1
G |  78   0  96  96   0   4  24   3   0   0   0   0   3   7  24   0   1   4   1  24  24   0   0   0   3   0  24  24  88
T |   5   0   0   0   0   1  24  82  96   0   0   0   6  11  24  96  88   1   1  24  24  72   0  96   3   0  24  24   3

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updated Mon Jan 5 01:23:17 2026