2o93_LMO : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF NFAT BOUND TO THE HIV-1 LTR TANDEM KAPPAB ENHANCER ELEMENT
reference	Bates et al. Structure 16 684 2008
source	Homo sapiens
experiment	X-ray (resolution=3.05, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;"Winged helix" DNA-binding domain;
reference complex	1p7h_L 3qrf_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o93_L interface=30,33,36,39,180,183,274, assvplewplssqsgsyelrievqpkphhRahYetEgsRgavkaptgghpvvqlhgymenkplglqifigtaderilkphafyqvhritgktvtttsyekivgntkvleiplepknnmratidcagilklrnadielrkgetdigrkntrvrlvfrvhipessgrivslqtasnpiecsQrsAhelpmverqdtdsclvyggqqmiltgqnftseskvvftekttdgqqiwemeatvdkdksqpnmlfveipeyrnkhirtpvkvnfyvingkRkrsqpqhftyhpv > 2o93_M interface=27,30,33,36,88,143,177, vplewplssqsgsyelrievqpkphhRahYetEgsRgavkaptgghpvvqlhgymenkplglqifigtaderilkphafyqvhritgKtvtttsyekivgntkvleiplepknnmratidcagilklrnadielrkgetdigRkntrvrlvfrvhipessgrivslqtasnpiecsQrsahelpmverqdtdsclvyggqqmiltgqnftseskvvftekttdgqqiwemeatvdkdksqpnmlfveipeyrnkhirtpvkvnfyvingkrkrsqpqhftyhpv > 2o93_O interface=30,33,35,36,39,180,181, assvplewplssqsgsyelrievqpkphhRahYeTEgsRgavkaptgghpvvqlhgymenkplglqifigtaderilkphafyqvhritgktvtttsyekivgntkvleiplepknnmratidcagilklrnadielrkgetdigrkntrvrlvfrvhipessgrivslqtasnpiecsQRsahelpmverqdtdsclvyggqqmiltgqnftseskvvftekttdgqqiwemeatvdkdksqpnmlfveipeyrnkhirtpvkvnfyvingkrkrsqpqhftyhpv
interface signature	RYERQAR/RYERKRQ/RYTERQR

Estimated binding specificities ?

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# IC=14.242 IC/col=0.593 n_of_columns=24

specificity:

A |   0   0   0  73  24  24   9   0   0   0   7  24  24  24  24  24  24  24  24  24   7   0   0   0
C |   0   0   0   7  24  24   7   0  96  96   7  24  24  24  24  24  24  24  24  24   7   0  96  96
G |  96  96  96   9  24  24   7   0   0   0  73  24  24  24  24  24  24  24  24  24   9   0   0   0
T |   0   0   0   7  24  24  73  96   0   0   9  24  24  24  24  24  24  24  24  24  73  96   0   0

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updated Mon Sep 9 15:49:15 2024