1p7h_L : 3D-footprint complex

structure name	STRUCTURE OF NFAT1 BOUND AS A DIMER TO THE HIV-1 LTR KB ELEMENT (Nuclear factor of activated T-cells, cytoplasmic 2)
reference	von Koenig et al. Nat.Struct.Biol. 10 800 2003
source	Homo sapiens
experiment	X-ray (resolution=2.60, R-factor=0.231)
structural superfamily	p53-like transcription factors;E set domains;
sequence family	Rel homology domain RHD; IPT/TIG domain;
multimeric complexes	1a02_FJN 1p7h_LN 1pzu_BHIM 1s9k_CDE 2o93_LMO
redundant complexes	1owr_P 1pzu_M 2as5_N 2o93_O 8ow4_B 1a02 1s9k 3qrf
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1p7h_L interface=29,32,34,35,38,145,179,272,273, ssvplewplssqsgsyelrievqpkphhRahYeTEgsRgavkaptgghpvvqlhgymenkplglqifigtaderilkphafyqvhritgktvtttsyekivgntkvleiplepknnmratidcagilklrnadielrkgetdigRkntrvrlvfrvhipessgrivslqtasnpiecsQrsahelpmverqdtdsclvyggqqmiltgqnftseskvvftekttdgqqiwemeatvdkdksqpnmlfveipeyrnkhirtpvkvnfyvingKRkrsqpqhftyhpv
interface signature	RYTERRQKR

Estimated binding specificities ?

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# IC=3.934 IC/col=0.983 n_of_columns=4

specificity:

A |   0   1  94  47
C |   1   0   0  17
G |  95  95   0  16
T |   0   0   2  16

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RG--YTTTECRG--QA----   L                  +--------------1imh_C    
                                            ! 
  RGRG--EC----RGPT----   L   +--------------4              +2ram_A    
                             !              !    +---------1 
  RGRGYTEC----RT------   L   !              !    !         +1gji_A    
                             !              +----3 
  RGRGYAEC--HGKG------   L --5                   !        +7w7l_B    
                             !                   +--------2 
  ------------------RG   L   !                            +1svc_P    
                             ! 
  ----------------FG--   L   +-----------------------------6f59_B

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updated Fri Sep 13 15:55:21 2024