1p7h_L : 3D-footprint complex

structure name	STRUCTURE OF NFAT1 BOUND AS A DIMER TO THE HIV-1 LTR KB ELEMENT (Nuclear factor of activated T-cells, cytoplasmic 2)
reference	von Koenig et al. Nat.Struct.Biol. 10 800 2003
source	Homo sapiens
experiment	X-ray (resolution=2.60, R-factor=0.231)
structural superfamily	p53-like transcription factors;E set domains;
sequence family	Rel homology domain RHD; IPT/TIG domain;
multimeric complexes	1a02_FJN 1p7h_LN 1pzu_BHIM 1s9k_CDE 2o93_LMO
redundant complexes	1owr_P 1pzu_M 2as5_N 2o93_O 8ow4_B 1a02 1s9k 3qrf
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1p7h_L interface=29,32,34,35,38,145,179,272,273, ssvplewplssqsgsyelrievqpkphhRahYeTEgsRgavkaptgghpvvqlhgymenkplglqifigtaderilkphafyqvhritgktvtttsyekivgntkvleiplepknnmratidcagilklrnadielrkgetdigRkntrvrlvfrvhipessgrivslqtasnpiecsQrsahelpmverqdtdsclvyggqqmiltgqnftseskvvftekttdgqqiwemeatvdkdksqpnmlfveipeyrnkhirtpvkvnfyvingKRkrsqpqhftyhpv
interface signature	RYTERRQKR

Estimated binding specificities ?

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# IC=4.026 IC/col=1.006 n_of_columns=4

specificity:

A |  17   0   0   0
C |  16   1  96  95
G |  16   0   0   1
T |  47  95   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RGRGYTECHG------   L   +-----------------------------2o61_B    
                         ! 
  ------------PTRG   L --3                             +1nfk_A    
                         !              +--------------1 
  --------------RG   L   +--------------2              +1svc_P    
                                        ! 
  RGRGYTECHGKG----   L                  +--------------1a3q_A

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updated Mon Jun 29 14:34:30 2026