2qby_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A HETERODIMER OF CDC6/ORC1 INITIATORS BOUND TO ORIGIN DNA (FROM S. SOLFATARICUS)
reference	Cunningham Dueber et al. Science 317 1210 2007
source	SULFOLOBUS SOLFATARICUS
experiment	X-ray (resolution=3.35, R-factor=?)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;"Winged helix" DNA-binding domain;
reference complex	2qby_A 2qby_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2qby_A interface=106,316,318,321,342,345, ifinreyllpdyipdelphredqirkiasilaplyreekpnnifiygltgtgktavvkfvlsklhkkflgkfkhvyintrqidtpyrvladllesldvkvpftglSiaelyrrlvkavrdygsqvvivldeidafvkkynddilyklsrinsevnkisfigitndvkfvdlldprvksslseeeiifppynaeelediltkraqmafkpgvlpdnviklcaalaarehgdarraldllrvsgeiaermkdtkvkeeyvymakeeierdrvrdiiltlpfhsklvlmavvsisvsttgavyetylnickklgveavTqRrvSdiineldmvgiltakvvnrgRygKtkeiglavdkniivrsliesd > 2qby_B interface=313,315,336,339,343, knpkvfidplsvfkeipfredilrdaaiairyfvknevkfsnlflgltgtgktfvskyifneieevkkedeeykdvkqayvncrevggtpqavlsslagkltgfsvpkhginlgeyidkikngtrniraiiyldevdtlvkrrggdivlyqllrsdanisvimisndinvrdymeprvlsslgpsvifkpydaeqlkfilskyaeyglikgtyddeilsyiaaisakehgdarkavnllfraaqlasgggiirkehvdkaivdyeqerlieavkalpfhyklalrsliesedvmsahkmytdlcnkfkqkplSyRrfsdiiseldmfgivkiriiNrgRaggVkkyalvedkekvlralnetfedsis
interface signature	STRSRK/SRNRV

Estimated binding specificities ?

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# IC=10.379 IC/col=0.649 n_of_columns=16

specificity:

A |   9  24  24  24  14   0   0  24  24   7   0  24   0   7   0  96
C |   7  24  24  24   9  96  96  24  24  66   0  24   0   0  96   0
G |   7  24  24  24  14   0   0  24  24   7  96  24   0   0   0   0
T |  73  24  24  24  59   0   0  24  24  16   0  24  96  89   0   0

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updated Tue Jul 29 18:39:37 2025