2qby_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A HETERODIMER OF CDC6/ORC1 INITIATORS BOUND TO ORIGIN DNA (FROM S. SOLFATARICUS) (CELL DIVISION CONTROL PROTEIN 6 HOMOLOG 1)
reference	Cunningham Dueber et al. Science 317 1210 2007
source	SULFOLOBUS SOLFATARICUS
experiment	X-ray (resolution=3.35, R-factor=0.226)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;"Winged helix" DNA-binding domain;
sequence family	CDC6, C terminal; ATPase family associated with various cellul;
multimeric complexes	2qby_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2qby_A interface=106,316,318,321,342,345, ifinreyllpdyipdelphredqirkiasilaplyreekpnnifiygltgtgktavvkfvlsklhkkflgkfkhvyintrqidtpyrvladllesldvkvpftglSiaelyrrlvkavrdygsqvvivldeidafvkkynddilyklsrinsevnkisfigitndvkfvdlldprvksslseeeiifppynaeelediltkraqmafkpgvlpdnviklcaalaarehgdarraldllrvsgeiaermkdtkvkeeyvymakeeierdrvrdiiltlpfhsklvlmavvsisvsttgavyetylnickklgveavTqRrvSdiineldmvgiltakvvnrgRygKtkeiglavdkniivrsliesd
interface signature	STRSRK

Estimated binding specificities ?

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# IC=2.046 IC/col=0.292 n_of_columns=7

specificity:

A |  38  24  24   0  12  60  38
C |  19  24  24   0  12  12  19
G |  20  24  24   0  60  12  20
T |  19  24  24  96  12  12  19

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----------TTKATTQTTG--LTRT----KAFTYT   L       +-----------------------------2p7c_B    
                                               +-1 
  ------------------NASTHT--STLT------   L   +-2 +-----------------------------7cby_C    
                                             ! ! 
  ----------------------YG------------     --3 +-----------------------------3eyi_B    
                                             ! 
  NGSGWGFARA--------------------------       +-----------------------------7aud_E

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updated Fri Sep 13 16:37:23 2024