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legend  pdf

structure nameMOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS
(DNA ENDONUCLEASE I-CREI)
referenceCabaniols et al. Nature 456 107 2008
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=1.80, R-factor=0.153)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes2vbj_AB 2vbo_AB
redundant complexes2vbj
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQESYRKKTSVNKT

Estimated binding specificities ?

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# IC=9.225 IC/col=1.025 n_of_columns=9 specificity:   
A |  65  21  10  85   0   0   0   0  96
C |  10   0  10   0   0  96  96   0   0
G |   0  74  55  11   0   0   0   0   0
T |  21   1  21   0  96   0   0  96   0
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updated Sun Aug 3 06:33:47 2025