3dlh_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE GUIDE-STRAND-CONTAINING ARGONAUTE PROTEIN SILENCING COMPLEX (ARGONAUTE)
reference	Patel et al. Nature 456 209 2008
source	THERMUS THERMOPHILUS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 566;
redundant complexes	3f73
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3dlh_A interface=128,170,198,215,216,224,244,250,252,253,264,265,275,408,410,413,429,431,440,441,444,536,564,598,603,635, hlgktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrmgdglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerlrrlegvwvEglavyrrehargpgwrvlggavldlwvsdsgafllevdpayRilcemsleawlaqghplpkrvrnaydrRtwellrlgeedpkelpLPgglslldYhaskgrlqgreggrvawvaDpkdprKpIPhltgllvpvlTLedlheslalSlpweerrrrtreiaswigrrlglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppMaWedRnrlkalllreglpsqIlNvplreeerHRweNallgllakaglqvvalsgaypaelavgfdaggresfrfggaacavggghllwtlperipqevvwdlleetlwafrrkagrlpsrvlllrdgRvpqdefalalealaregiaydlvsvrkSgggrvypvqgrladglyvpledktfllltvhrdFrgtpRplklvheagdtplealahqifhltrlypasgFafprlpaplhladrlvkevgrlgirhlkevdreklffv
interface signature	ERRLPYDKIPTLSMWRINHRNRSFRF

Estimated binding specificities ?

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# IC=11.330 IC/col=0.666 n_of_columns=17

specificity:

A |   0   0  31  24  21  12  96   0   7  96   0  24  24  24  60   4   0
C |   0   0  21  24  21  12   0   0   8   0   0  24  24  24  12   4   0
G |   0  96  21  24  33  12   0  96   7   0  96  24  24  24  12  81   0
T |  96   0  23  24  21  60   0   0  74   0   0  24  24  24  12   7  96

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updated Mon Dec 16 20:42:33 2024