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structure nameCRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE N546 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 12-NT RNA TARGET STRAND
(ARGONAUTE)
referencePatel et al. Nature 461 754 2009
sourceTHERMUS THERMOPHILUS
experimentX-ray (resolution=2.60, R-factor=?)
structural superfamilyRibonuclease H-like;
sequence familyPiwi domain 534;
multimeric complexes3hk2_AB 3hvr_AB
redundant complexes3hm9 3hvr 3dlh 3hk2 3f73 3hxm 3hjf
reference complex4n41_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYKILMWRINHRNRRF

Estimated binding specificities ?

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# IC=7.099 IC/col=0.473 n_of_columns=15 specificity:   
A |   0   0  24  24  24  13  54   0  24  24  24  24  24   0   0
C |   0   0  24  24  24  13  13   0  24  24  24  24  24   0   0
G |   0  96  24  24  24  16  16  96  24  24  24  24  24  96   0
T |  96   0  24  24  24  54  13   0  24  24  24  24  24   0  96
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updated Sat Aug 2 03:58:56 2025