3hxm_A : 3D-footprint complex

structure name	STRUCTURE OF AN ARGONAUTE COMPLEXED WITH GUIDE DNA AND TARGET RNA DUPLEX CONTAINING TWO MISMATCHES. (ARGONAUTE)
reference	Patel et al. Nature 461 754 2009
source	THERMUS THERMOPHILUS
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	Ribonuclease H-like;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3hxm_A interface=213,366,368,371,387,389,398,399,402,567,599, gktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrmgdglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerlrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsleawlaqghplpkrvrnaydrrtwellrlgeedpslldYhaskgrvpvltledlhealslpweerrrrtreiaswigrrlglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppMaWedRnrlkalllreglpsqIlNvplreeerHRweNallgllakaglqvvalsgaypaelavgfdaggresfrfggaacavgggghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvlllrdgrvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfllltvhrdfrgtpRplklvheagdtplealahqifhltrlypasgFafprlpaplhladrlvkevgrlgirhlkevdreklffv
interface signature	YMWRINHRNRF

Estimated binding specificities ?

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# IC=4.707 IC/col=0.362 n_of_columns=13

specificity:

A |   0   0  31  24  24  16  74  24  24  24  24  24   0
C |   0   0  21  24  24  16   8  24  24  24  24  24   0
G |   0  96  21  24  24  19   7  24  24  24  24  24   0
T |  96   0  23  24  24  45   7  24  24  24  24  24  96

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updated Mon Dec 16 21:01:57 2024