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legend  pdf

structure nameTHREE CONFORMATIONAL SNAPSHOTS OF THE HEPATITIS C VIRUS NS3 HELICASE REVEAL A RATCHET TRANSLOCATION MECHANISM
(Serine proteaseNTPasehelicase NS3)
referenceRice et al. Proc.Natl.Acad.Sci.USA 107 521 2010
sourceHepatitis C virus
experimentX-ray (resolution=2.80, R-factor=?)
structural superfamilyP-loop containing nucleoside triphosphate hydrolases;
multimeric complexes3kqu_ABC 3kqu_DEF
reference complex3kqh_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTHRVQTTTWYN

Estimated binding specificities ?

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# IC=5.807 IC/col=0.968 n_of_columns=6 specificity:   
A |   0   0  13   0  13   0
C |   0   0  13   0  16   0
G |   0   0  13   0  13   0
T |  96  96  57  96  54  96
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updated Sat Aug 2 04:14:09 2025