3wtt_AC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF PHOSPHORYLATED ETS1, RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
reference	Shiina et al. J.Mol.Biol. 427 1655 2015
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.35, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;p53-like transcription factors;
reference complex	2stt_A 4l18_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3wtt_A interface=21,83,111,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvakgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRr > 3wtt_C interface=69,70,73,76,77, pvipaaalagytgsgpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvk
interface signature	RRVDRR/EKRRY

Estimated binding specificities ?

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# IC=12.872 IC/col=1.073 n_of_columns=12

specificity:

A |  54  48   6   0   0  96   0  96   0   0   0   0
C |  13  20  16  96  96   0  96   0   0  96  96   0
G |  13   8  68   0   0   0   0   0   0   0   0   0
T |  16  20   6   0   0   0   0   0  96   0   0  96

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updated Wed Jun 24 19:39:44 2026