3wtx_AC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1(Y329A), RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
reference	Shiina et al. J.Mol.Biol. 427 1655 2015
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;"Winged helix" DNA-binding domain;
reference complex	3wts_A 4l18_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3wtx_A interface=21,83,111,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvakgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepR > 3wtx_C interface=55,58,61,62, piqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvk
interface signature	RRVDRR/KRRY

Estimated binding specificities ?

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# IC=10.397 IC/col=1.040 n_of_columns=10

specificity:

A |  72   0   0  88   0   0   8   0   0   8
C |   8   0   0   8   8   0   8   0   0  72
G |   8  96  96   0   0  96   8  96  96   8
T |   8   0   0   0  88   0  72   0   0   8

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updated Wed Jul 30 00:06:16 2025