Estimated binding specificities ?

structure nameSTRUCTURE OF E. COLI EXONUCLEASE I IN COMPLEX WITH A 5CY-DT13 OLIGONUCLEOTIDE
(Exodeoxyribonuclease I)
reference'Nucleic 41 5887 2013
sourceEscherichia coli
experimentX-ray (resolution=1.95, R-factor=0.215)
structural superfamilyRibonuclease H-like;
sequence familyExonuclease Cterminal;
multimeric complexes4hcb_AB 4hcc_AB 4jrp_AB 4jrq_AB 4js4_AB 4js5_AB
redundant complexes4hcb_A 4hcc_B 4jrq_B 4js4_A 4js5_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
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# IC=13.761 IC/col=1.059 n_of_columns=13 specificity:   
A |   0   0   0   0  16   0   0   0   0  24  13   0   0
C |   0   0   0   0  13   0   0   0   0  24  16   0   0
G |   0   0   0   0  13   0   0   0   0  24  13   0   0
T |  96  96  96  96  54  96  96  96  96  24  54  96  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  TT--ATITNT--FT--YTDTFTTTNTHTKTMTATMTNTRTNTLTYTSTYTNTFT   L        +----------------------4jrp_A    
                                                               +----2 
  ----------EC------------------------------------------       !    !            +---------3qex_A    
                                                             --3    +------------1 
  --QT--------------------------------------------------       !                 +---------8d0b_F    
                                                               ! 
  --QT----------KT--------------------------------------       +---------------------------8d0k_F

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updated Sun Aug 3 08:11:16 2025