4l18_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 3)
reference	Leukemia 28 2040 2014
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;p53-like transcription factors;
reference complex	4l18_B 4l18_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4l18_A interface=28,90,118,119,122,125, evladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRpgslsfserlseleqlr > 4l18_B interface=56,59,62,63, gpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvkpda
interface signature	RRVDRR/KRRY

Estimated binding specificities ?

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# IC=13.652 IC/col=1.138 n_of_columns=12

specificity:

A |  82  68  54   0   0  96   0  96   0   0   0   0
C |   0  13  13  96  96   0  96   0   0  96  96   0
G |   0   2  16   0   0   0   0   0   0   0   0   0
T |  14  13  13   0   0   0   0   0  96   0   0  96

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updated Wed Jul 30 02:04:43 2025