4l18_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 3)
reference	Leukemia 28 2040 2014
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;p53-like transcription factors;
reference complex	2stt_A 4l18_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4l18_A interface=28,90,118,119,122,125, evladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRpgslsfserlseleqlr > 4l18_B interface=56,59,62,63, gpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvkpda
interface signature	RRVDRR/KRRY

Estimated binding specificities ?

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# IC=12.245 IC/col=1.020 n_of_columns=12

specificity:

A |  84  60  24   0   0  96   0  96   0   0   0  12
C |   0  12  24  96  96   0  96   0   0  96  96  12
G |   0  12  24   0   0   0   0   0   0   0   0  12
T |  12  12  24   0   0   0   0   0  96   0   0  60

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updated Wed Jun 24 21:50:50 2026